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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IER5L
All Species:
14.55
Human Site:
S222
Identified Species:
40
UniProt:
Q5T953
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T953
NP_982258.2
404
42109
S222
A
P
P
A
A
A
A
S
P
P
A
S
P
A
P
Chimpanzee
Pan troglodytes
XP_520307
238
26159
D88
G
M
P
A
S
A
A
D
F
G
P
L
Q
L
G
Rhesus Macaque
Macaca mulatta
XP_001118694
558
58361
S376
A
P
P
A
A
A
A
S
P
P
A
S
P
A
P
Dog
Lupus familis
XP_548423
409
42715
S227
P
Q
A
A
A
G
A
S
P
P
A
S
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99J55
406
42511
S225
P
S
T
V
A
A
S
S
P
P
A
S
T
A
P
Rat
Rattus norvegicus
Q5PQP0
409
42854
S227
P
P
T
V
A
A
S
S
P
P
A
S
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517786
265
27117
A115
A
Q
S
G
E
G
G
A
G
G
G
S
S
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66IT9
293
31857
K125
A
H
S
P
H
P
A
K
E
P
Q
S
H
A
A
Zebra Danio
Brachydanio rerio
Q6NYT3
301
32920
A140
S
E
E
V
C
K
A
A
P
E
P
S
F
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.6
50.5
95.5
N.A.
94.5
94.3
N.A.
26.7
N.A.
47
45
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.4
57.1
96
N.A.
95.3
95.5
N.A.
33.6
N.A.
52.2
52.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
100
73.3
N.A.
60
73.3
N.A.
13.3
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
73.3
N.A.
66.6
80
N.A.
20
N.A.
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
12
45
56
56
67
23
0
0
56
0
0
67
23
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
12
12
0
12
0
0
0
12
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% F
% Gly:
12
0
0
12
0
23
12
0
12
23
12
0
0
0
12
% G
% His:
0
12
0
0
12
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
34
34
12
0
12
0
0
67
67
23
0
45
12
56
% P
% Gln:
0
23
0
0
0
0
0
0
0
0
12
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
12
12
23
0
12
0
23
56
0
0
0
89
12
0
0
% S
% Thr:
0
0
23
0
0
0
0
0
0
0
0
0
12
0
0
% T
% Val:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _