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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IER5L All Species: 24.55
Human Site: T255 Identified Species: 67.5
UniProt: Q5T953 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T953 NP_982258.2 404 42109 T255 L H C S S Q T T V L D L D T H
Chimpanzee Pan troglodytes XP_520307 238 26159 Q121 L H Q L H L Q Q Q L H Q H Q H
Rhesus Macaque Macaca mulatta XP_001118694 558 58361 T409 L H C S S Q T T V L D L D T H
Dog Lupus familis XP_548423 409 42715 T260 V H C S S Q T T V L D L D T H
Cat Felis silvestris
Mouse Mus musculus Q99J55 406 42511 T258 V H C S S Q T T V L D L D T H
Rat Rattus norvegicus Q5PQP0 409 42854 T260 V H C S S Q T T V L D L D T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517786 265 27117 P148 C R R C C D L P G D G G G G S
Chicken Gallus gallus
Frog Xenopus laevis Q66IT9 293 31857 T158 P P Q C S H T T V L D L D T H
Zebra Danio Brachydanio rerio Q6NYT3 301 32920 T173 N M H C N K T T V L D L D T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.6 50.5 95.5 N.A. 94.5 94.3 N.A. 26.7 N.A. 47 45 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 58.4 57.1 96 N.A. 95.3 95.5 N.A. 33.6 N.A. 52.2 52.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 100 93.3 N.A. 93.3 93.3 N.A. 0 N.A. 66.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 0 N.A. 66.6 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 12 0 56 34 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 0 12 78 0 78 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 0 12 12 12 12 0 % G
% His: 0 67 12 0 12 12 0 0 0 0 12 0 12 0 89 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % K
% Leu: 34 0 0 12 0 12 12 0 0 89 0 78 0 0 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % P
% Gln: 0 0 23 0 0 56 12 12 12 0 0 12 0 12 0 % Q
% Arg: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 56 67 0 0 0 0 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 0 78 78 0 0 0 0 0 78 0 % T
% Val: 34 0 0 0 0 0 0 0 78 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _