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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP5KL1
All Species:
13.94
Human Site:
S25
Identified Species:
51.11
UniProt:
Q5T9C9
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9C9
NP_001128691.1
394
44572
S25
A
G
C
R
A
V
T
S
S
R
R
G
L
L
W
Chimpanzee
Pan troglodytes
XP_520281
394
44454
S25
A
G
C
R
A
V
T
S
S
R
R
G
L
L
W
Rhesus Macaque
Macaca mulatta
XP_001094094
477
52569
S108
A
G
C
R
A
V
T
S
S
R
R
G
L
L
W
Dog
Lupus familis
XP_851419
715
78516
S346
C
R
A
A
T
S
T
S
G
R
C
G
L
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6U7H8
395
45274
S27
N
K
S
I
S
S
G
S
R
R
G
L
L
W
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5PQ01
419
47633
T31
A
T
T
A
K
T
K
T
K
K
K
H
F
V
Q
Zebra Danio
Brachydanio rerio
XP_001923992
388
45710
Q25
R
R
W
G
G
L
R
Q
Q
W
K
L
L
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
80
50.3
N.A.
72.9
N.A.
N.A.
N.A.
N.A.
23.8
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
81.1
53
N.A.
84
N.A.
N.A.
N.A.
N.A.
43.9
73
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
15
29
43
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
43
0
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
43
0
15
15
0
15
0
15
0
15
58
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
15
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
0
15
0
15
0
15
15
29
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
0
0
0
0
0
29
86
58
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
15
15
0
0
0
0
0
15
% Q
% Arg:
15
29
0
43
0
0
15
0
15
72
43
0
0
0
0
% R
% Ser:
0
0
15
0
15
29
0
72
43
0
0
0
0
0
0
% S
% Thr:
0
15
15
0
15
15
58
15
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
43
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
15
0
0
0
0
0
0
15
0
0
0
15
58
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _