KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC18
All Species:
13.03
Human Site:
S35
Identified Species:
26.06
UniProt:
Q5T9S5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9S5
NP_996769.2
1454
168962
S35
E
L
K
I
T
E
W
S
L
Q
S
L
G
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537071
1456
169626
S35
E
L
K
I
T
E
W
S
L
Q
S
L
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q640L5
1455
169723
S37
E
L
K
I
T
E
W
S
L
H
N
L
G
E
E
Rat
Rattus norvegicus
XP_001060717
1462
170487
S36
E
L
K
I
T
E
W
S
L
H
N
L
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508531
925
106760
Chicken
Gallus gallus
XP_001232490
1295
151316
V35
T
E
E
N
L
Q
S
V
G
A
E
L
S
S
T
Frog
Xenopus laevis
Q9PW73
1335
154049
D36
E
W
S
I
E
H
E
D
E
K
R
D
H
S
S
Zebra Danio
Brachydanio rerio
XP_692712
779
89837
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
P81
L
V
Q
E
M
N
P
P
K
F
E
K
T
E
D
Sea Urchin
Strong. purpuratus
XP_796315
2152
245292
Q57
G
V
P
E
E
D
D
Q
V
P
A
L
T
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
A179
R
P
L
K
A
R
S
A
L
I
S
L
P
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
84.4
83.5
N.A.
41.4
49.3
39.8
22.7
N.A.
N.A.
N.A.
20.2
22.9
Protein Similarity:
100
N.A.
N.A.
95.4
N.A.
92.4
91.4
N.A.
51
65.2
59.5
37.2
N.A.
N.A.
N.A.
40
40
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
0
6.6
13.3
0
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
0
20
20
0
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
9
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
9
0
0
0
9
0
0
17
% D
% Glu:
42
9
9
17
17
34
9
0
9
0
17
0
0
42
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
0
0
34
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
17
0
0
9
0
0
% H
% Ile:
0
0
0
42
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
34
9
0
0
0
0
9
9
0
9
0
0
0
% K
% Leu:
9
34
9
0
9
0
0
0
42
0
0
59
0
9
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
9
9
0
9
0
0
9
0
0
% P
% Gln:
0
0
9
0
0
9
0
9
0
17
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
17
34
0
0
25
0
9
17
17
% S
% Thr:
9
0
0
0
34
0
0
0
0
0
0
0
17
9
9
% T
% Val:
0
17
0
0
0
0
0
9
9
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
34
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _