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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC18
All Species:
15.76
Human Site:
S578
Identified Species:
31.52
UniProt:
Q5T9S5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9S5
NP_996769.2
1454
168962
S578
S
E
M
T
K
K
C
S
Q
L
L
T
L
E
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537071
1456
169626
S577
S
E
M
T
K
K
C
S
Q
L
L
T
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q640L5
1455
169723
S579
N
E
M
T
K
K
C
S
Q
L
L
I
L
E
K
Rat
Rattus norvegicus
XP_001060717
1462
170487
S582
N
E
M
T
K
K
C
S
Q
L
L
I
L
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508531
925
106760
V190
E
I
T
A
Q
D
K
V
L
R
D
A
E
D
K
Chicken
Gallus gallus
XP_001232490
1295
151316
T539
N
E
N
L
S
L
K
T
S
M
A
Q
R
T
S
Frog
Xenopus laevis
Q9PW73
1335
154049
D562
E
K
L
K
N
Y
K
D
Q
I
V
N
L
E
D
Zebra Danio
Brachydanio rerio
XP_692712
779
89837
D44
G
N
D
I
I
G
E
D
T
D
V
V
E
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
A946
A
D
N
E
D
R
T
A
D
V
Q
R
A
K
K
Sea Urchin
Strong. purpuratus
XP_796315
2152
245292
G620
K
E
L
K
K
A
K
G
K
I
S
A
L
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
T797
E
N
F
S
I
L
E
T
E
L
K
N
V
R
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
84.4
83.5
N.A.
41.4
49.3
39.8
22.7
N.A.
N.A.
N.A.
20.2
22.9
Protein Similarity:
100
N.A.
N.A.
95.4
N.A.
92.4
91.4
N.A.
51
65.2
59.5
37.2
N.A.
N.A.
N.A.
40
40
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
6.6
6.6
20
0
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
20
26.6
46.6
6.6
N.A.
N.A.
N.A.
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
0
9
0
0
9
17
9
9
0
% A
% Cys:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
9
0
17
9
9
9
0
0
9
17
% D
% Glu:
25
50
0
9
0
0
17
0
9
0
0
0
17
50
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
9
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
17
0
0
0
0
17
0
17
0
0
0
% I
% Lys:
9
9
0
17
42
34
34
0
9
0
9
0
0
9
50
% K
% Leu:
0
0
17
9
0
17
0
0
9
42
34
0
50
0
0
% L
% Met:
0
0
34
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
25
17
17
0
9
0
0
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
42
0
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
9
0
9
9
9
0
% R
% Ser:
17
0
0
9
9
0
0
34
9
0
9
0
0
0
9
% S
% Thr:
0
0
9
34
0
0
9
17
9
0
0
17
0
9
9
% T
% Val:
0
0
0
0
0
0
0
9
0
9
17
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _