Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC18 All Species: 7.88
Human Site: T1444 Identified Species: 15.76
UniProt: Q5T9S5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T9S5 NP_996769.2 1454 168962 T1444 L K K S S M Q T G A G L N Q G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537071 1456 169626 T1443 L K K S S M Q T G A G L P Q T
Cat Felis silvestris
Mouse Mus musculus Q640L5 1455 169723 T1445 L K K S S L Q T A T G L S Q G
Rat Rattus norvegicus XP_001060717 1462 170487 A1448 L K K P P L Q A A T G L S Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508531 925 106760 M918 Q S R C C P K M A W T R L G D
Chicken Gallus gallus XP_001232490 1295 151316 L1288 V R A A S E T L L V K V R E L
Frog Xenopus laevis Q9PW73 1335 154049 G1328 H S P S K A A G I D G G S L G
Zebra Danio Brachydanio rerio XP_692712 779 89837 A772 Q K K E R Q A A E L S G S I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P02566 1966 225108 V1954 Q S S A S A A V I R S P S R A
Sea Urchin Strong. purpuratus XP_796315 2152 245292 K2056 T R R A L F S K G G S S Q T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LW85 726 81954 R719 T V K K V V R R R K S S T S S
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 L1765 Y R S K L K D L G V E I S S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.1 N.A. 84.4 83.5 N.A. 41.4 49.3 39.8 22.7 N.A. N.A. N.A. 20.2 22.9
Protein Similarity: 100 N.A. N.A. 95.4 N.A. 92.4 91.4 N.A. 51 65.2 59.5 37.2 N.A. N.A. N.A. 40 40
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 73.3 46.6 N.A. 0 6.6 20 13.3 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 86.6 60 N.A. 13.3 40 26.6 20 N.A. N.A. N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 22.4 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 25 0 17 25 17 25 17 0 0 0 0 25 % A
% Cys: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 17 % D
% Glu: 0 0 0 9 0 9 0 0 9 0 9 0 0 9 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 34 9 42 17 0 9 25 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 9 0 9 0 % I
% Lys: 0 42 50 17 9 9 9 9 0 9 9 0 0 0 0 % K
% Leu: 34 0 0 0 17 17 0 17 9 9 0 34 9 9 9 % L
% Met: 0 0 0 0 0 17 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 9 9 9 9 0 0 0 0 0 9 9 0 0 % P
% Gln: 25 0 0 0 0 9 34 0 0 0 0 0 9 34 0 % Q
% Arg: 0 25 17 0 9 0 9 9 9 9 0 9 9 9 0 % R
% Ser: 0 25 17 34 42 0 9 0 0 0 34 17 50 17 9 % S
% Thr: 17 0 0 0 0 0 9 25 0 17 9 0 9 9 17 % T
% Val: 9 9 0 0 9 9 0 9 0 17 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _