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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TEDDM1 All Species: 17.58
Human Site: T145 Identified Species: 42.96
UniProt: Q5T9Z0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T9Z0 NP_741997.3 273 31315 T145 F L L L L V L T A E L W A P N
Chimpanzee Pan troglodytes XP_524988 301 34454 T173 F L L L L V L T A E L W A P N
Rhesus Macaque Macaca mulatta XP_001114699 274 31266 T145 F L L L L V L T A Q L W A P N
Dog Lupus familis XP_855573 257 30326 G131 R C A A L E Q G A Q A L G I F
Cat Felis silvestris
Mouse Mus musculus Q810U2 305 34776 T173 F L L M L V L T A E L W A P E
Rat Rattus norvegicus Q8CHM9 305 34847 T173 F L L M L V L T A E L W A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506350 563 61793 F350 F G G T L T I F L E V L L R D
Chicken Gallus gallus
Frog Xenopus laevis Q6NS09 280 31983 R143 F Y Y H V H N R P A L D Q H I
Zebra Danio Brachydanio rerio Q6P0S3 283 32742 H154 E P L D Q H I H S L L L F A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780239 288 32569 M157 Q L H T M L V M A I F V C F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.4 94.1 42.4 N.A. 61.6 59.3 N.A. 20.2 N.A. 28.2 26.5 N.A. N.A. N.A. N.A. 22.5
Protein Similarity: 100 85.3 97.4 58.6 N.A. 72.1 71.1 N.A. 30.3 N.A. 47.5 43.4 N.A. N.A. N.A. N.A. 41.3
P-Site Identity: 100 100 93.3 13.3 N.A. 86.6 86.6 N.A. 20 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 93.3 93.3 N.A. 40 N.A. 20 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 70 10 10 0 50 10 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 10 % D
% Glu: 10 0 0 0 0 10 0 0 0 50 0 0 0 0 20 % E
% Phe: 70 0 0 0 0 0 0 10 0 0 10 0 10 10 10 % F
% Gly: 0 10 10 0 0 0 0 10 0 0 0 0 10 0 0 % G
% His: 0 0 10 10 0 20 0 10 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 20 0 0 10 0 0 0 10 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 60 60 30 70 10 50 0 10 10 70 30 10 0 10 % L
% Met: 0 0 0 20 10 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 30 % N
% Pro: 0 10 0 0 0 0 0 0 10 0 0 0 0 50 0 % P
% Gln: 10 0 0 0 10 0 10 0 0 20 0 0 10 0 0 % Q
% Arg: 10 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 20 0 10 0 50 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 50 10 0 0 0 10 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _