KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TEDDM1
All Species:
10.61
Human Site:
Y250
Identified Species:
25.93
UniProt:
Q5T9Z0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9Z0
NP_741997.3
273
31315
Y250
A
S
T
P
G
P
L
Y
K
L
L
Q
E
V
E
Chimpanzee
Pan troglodytes
XP_524988
301
34454
Y278
A
S
T
P
G
P
L
Y
K
L
L
Q
E
V
E
Rhesus Macaque
Macaca mulatta
XP_001114699
274
31266
L250
A
S
T
P
G
G
P
L
Y
K
L
L
Q
E
V
Dog
Lupus familis
XP_855573
257
30326
V235
T
T
F
F
C
W
H
V
A
F
I
A
I
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q810U2
305
34776
Y278
E
S
S
S
G
T
F
Y
K
L
L
Q
E
A
E
Rat
Rattus norvegicus
Q8CHM9
305
34847
Y278
K
S
S
E
G
T
F
Y
K
L
L
Q
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506350
563
61793
A455
S
D
K
N
V
H
M
A
L
L
Q
D
L
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NS09
280
31983
K250
Y
C
V
N
R
H
K
K
L
P
V
I
V
D
N
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
E259
R
R
Q
R
G
D
M
E
M
G
L
R
K
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780239
288
32569
E265
Q
M
S
N
G
P
E
E
H
E
V
K
L
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
94.1
42.4
N.A.
61.6
59.3
N.A.
20.2
N.A.
28.2
26.5
N.A.
N.A.
N.A.
N.A.
22.5
Protein Similarity:
100
85.3
97.4
58.6
N.A.
72.1
71.1
N.A.
30.3
N.A.
47.5
43.4
N.A.
N.A.
N.A.
N.A.
41.3
P-Site Identity:
100
100
40
0
N.A.
60
53.3
N.A.
13.3
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
46.6
20
N.A.
66.6
66.6
N.A.
26.6
N.A.
6.6
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
0
0
0
10
10
0
0
10
0
20
0
% A
% Cys:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
0
0
0
0
10
0
10
0
% D
% Glu:
10
0
0
10
0
0
10
20
0
10
0
0
30
20
50
% E
% Phe:
0
0
10
10
0
0
20
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
70
10
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
20
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% I
% Lys:
10
0
10
0
0
0
10
10
40
10
0
10
20
0
0
% K
% Leu:
0
0
0
0
0
0
20
10
20
50
60
10
20
20
0
% L
% Met:
0
10
0
0
0
0
20
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
30
0
30
10
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
10
40
10
0
0
% Q
% Arg:
10
10
0
10
10
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
50
30
10
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
10
10
30
0
0
20
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
10
0
0
10
0
0
20
0
10
20
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
40
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _