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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF3L All Species: 26.36
Human Site: S172 Identified Species: 48.33
UniProt: Q5TA45 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TA45 NP_060341.2 600 67663 S172 Q I K V G S E S V V Y T G D Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092173 518 58516 V157 G G K V L I P V F A L G R A Q
Dog Lupus familis XP_536711 600 67738 S172 Q I K V G S E S V V Y T G D Y
Cat Felis silvestris
Mouse Mus musculus Q9CWS4 600 67825 S172 Q I K V G S E S V V Y T G D Y
Rat Rattus norvegicus Q3MHC2 600 67822 S172 Q I K V G S E S V V Y T G D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIH0 600 68170 S172 Q I K V G C E S V V Y T G D Y
Frog Xenopus laevis Q9W799 783 88968 E169 I V K D G E E E I V Y A V D F
Zebra Danio Brachydanio rerio Q503E1 598 67573 S172 Q I K V G S E S V V Y T G D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3D6 756 85400 D169 I V K V G E E D I V Y A T D F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_495706 608 68677 S176 E I R L G D H S V L Y T G D Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GUU3 613 67986 A171 Y A K M G D A A I V Y T G D Y
Baker's Yeast Sacchar. cerevisiae Q06224 779 87655 R178 Q I E I A G L R V L F T G D Y
Red Bread Mold Neurospora crassa Q8WZS6 850 94060 K188 L I E I A G L K I F F T G D Y
Conservation
Percent
Protein Identity: 100 N.A. 85.6 97.5 N.A. 97.1 97 N.A. N.A. 92 23.8 84 N.A. 23.6 N.A. 55.2 N.A.
Protein Similarity: 100 N.A. 86.1 98.5 N.A. 98.6 98.6 N.A. N.A. 95.8 41.2 92.6 N.A. 42.7 N.A. 72.5 N.A.
P-Site Identity: 100 N.A. 13.3 100 N.A. 100 100 N.A. N.A. 93.3 40 100 N.A. 46.6 N.A. 60 N.A.
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 100 N.A. N.A. 93.3 60 100 N.A. 66.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 45.5 28.7 24.8
Protein Similarity: N.A. N.A. N.A. 65.5 47.1 40.5
P-Site Identity: N.A. N.A. N.A. 53.3 46.6 33.3
P-Site Similarity: N.A. N.A. N.A. 73.3 73.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 16 0 8 8 0 8 0 16 0 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 16 0 8 0 0 0 0 0 93 0 % D
% Glu: 8 0 16 0 0 16 62 8 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 8 16 0 0 0 16 % F
% Gly: 8 8 0 0 77 16 0 0 0 0 0 8 77 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 16 70 0 16 0 8 0 0 31 0 0 0 0 0 0 % I
% Lys: 0 0 77 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 8 8 0 16 0 0 16 8 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 54 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 8 0 0 0 0 8 0 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 39 0 54 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 77 8 0 0 % T
% Val: 0 16 0 62 0 0 0 8 62 70 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 77 0 0 0 77 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _