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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3L
All Species:
15.15
Human Site:
T526
Identified Species:
27.78
UniProt:
Q5TA45
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TA45
NP_060341.2
600
67663
T526
D
T
R
K
E
Q
E
T
A
L
R
V
Y
S
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092173
518
58516
M444
D
T
R
K
E
Q
E
M
A
L
R
V
Y
S
H
Dog
Lupus familis
XP_536711
600
67738
M526
D
P
R
K
E
Q
E
M
A
V
R
V
Y
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWS4
600
67825
T526
D
T
R
K
E
Q
E
T
A
L
R
V
Y
S
H
Rat
Rattus norvegicus
Q3MHC2
600
67822
T526
D
T
R
K
E
Q
E
T
A
L
R
V
Y
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIH0
600
68170
T526
D
P
R
K
E
H
E
T
V
L
R
V
Y
N
H
Frog
Xenopus laevis
Q9W799
783
88968
I697
E
F
S
E
E
S
E
I
I
P
T
L
E
P
L
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
T525
L
H
D
P
H
S
D
T
D
T
L
S
R
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
T670
A
S
V
Q
E
G
K
T
L
T
L
E
T
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495706
608
68677
V528
E
I
I
K
G
K
K
V
N
W
K
E
L
S
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GUU3
613
67986
D534
K
G
E
S
E
D
D
D
V
D
L
I
K
Q
L
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
Q626
N
T
G
K
L
I
L
Q
I
M
G
D
I
K
L
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
L609
L
P
E
V
K
P
K
L
E
I
V
K
S
E
N
Conservation
Percent
Protein Identity:
100
N.A.
85.6
97.5
N.A.
97.1
97
N.A.
N.A.
92
23.8
84
N.A.
23.6
N.A.
55.2
N.A.
Protein Similarity:
100
N.A.
86.1
98.5
N.A.
98.6
98.6
N.A.
N.A.
95.8
41.2
92.6
N.A.
42.7
N.A.
72.5
N.A.
P-Site Identity:
100
N.A.
93.3
80
N.A.
100
100
N.A.
N.A.
73.3
13.3
6.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
100
100
N.A.
N.A.
80
33.3
20
N.A.
33.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
28.7
24.8
Protein Similarity:
N.A.
N.A.
N.A.
65.5
47.1
40.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
39
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
8
0
0
8
16
8
8
8
0
8
0
0
0
% D
% Glu:
16
0
16
8
70
0
54
0
8
0
0
16
8
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
8
8
0
0
0
0
8
0
0
0
0
% G
% His:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
47
% H
% Ile:
0
8
8
0
0
8
0
8
16
8
0
8
8
8
0
% I
% Lys:
8
0
0
62
8
8
24
0
0
0
8
8
8
8
0
% K
% Leu:
16
0
0
0
8
0
8
8
8
39
24
8
8
8
24
% L
% Met:
0
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
16
% N
% Pro:
0
24
0
8
0
8
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
8
0
39
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
47
0
0
0
0
0
0
0
47
0
8
0
0
% R
% Ser:
0
8
8
8
0
16
0
0
0
0
0
8
8
47
0
% S
% Thr:
0
39
0
0
0
0
0
47
0
16
8
0
8
0
0
% T
% Val:
0
0
8
8
0
0
0
8
16
8
8
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _