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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3L
All Species:
35.45
Human Site:
Y175
Identified Species:
65
UniProt:
Q5TA45
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TA45
NP_060341.2
600
67663
Y175
V
G
S
E
S
V
V
Y
T
G
D
Y
N
M
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092173
518
58516
L160
V
L
I
P
V
F
A
L
G
R
A
Q
E
L
C
Dog
Lupus familis
XP_536711
600
67738
Y175
V
G
S
E
S
V
V
Y
T
G
D
Y
N
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWS4
600
67825
Y175
V
G
S
E
S
V
V
Y
T
G
D
Y
N
M
T
Rat
Rattus norvegicus
Q3MHC2
600
67822
Y175
V
G
S
E
S
V
V
Y
T
G
D
Y
N
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIH0
600
68170
Y175
V
G
C
E
S
V
V
Y
T
G
D
Y
N
M
T
Frog
Xenopus laevis
Q9W799
783
88968
Y172
D
G
E
E
E
I
V
Y
A
V
D
F
N
H
K
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
Y175
V
G
S
E
S
V
V
Y
T
G
D
Y
N
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
Y172
V
G
E
E
D
I
V
Y
A
T
D
F
N
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495706
608
68677
Y179
L
G
D
H
S
V
L
Y
T
G
D
Y
N
M
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GUU3
613
67986
Y174
M
G
D
A
A
I
V
Y
T
G
D
Y
N
M
T
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
F181
I
A
G
L
R
V
L
F
T
G
D
Y
S
R
E
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
F191
I
A
G
L
K
I
F
F
T
G
D
Y
S
R
E
Conservation
Percent
Protein Identity:
100
N.A.
85.6
97.5
N.A.
97.1
97
N.A.
N.A.
92
23.8
84
N.A.
23.6
N.A.
55.2
N.A.
Protein Similarity:
100
N.A.
86.1
98.5
N.A.
98.6
98.6
N.A.
N.A.
95.8
41.2
92.6
N.A.
42.7
N.A.
72.5
N.A.
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
N.A.
93.3
40
100
N.A.
46.6
N.A.
73.3
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
93.3
53.3
100
N.A.
60
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
28.7
24.8
Protein Similarity:
N.A.
N.A.
N.A.
65.5
47.1
40.5
P-Site Identity:
N.A.
N.A.
N.A.
66.6
33.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
60
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
8
0
8
0
16
0
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
16
0
8
0
0
0
0
0
93
0
0
0
0
% D
% Glu:
0
0
16
62
8
0
0
0
0
0
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
8
8
16
0
0
0
16
0
0
0
% F
% Gly:
0
77
16
0
0
0
0
0
8
77
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
16
0
% H
% Ile:
16
0
8
0
0
31
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
16
% K
% Leu:
8
8
0
16
0
0
16
8
0
0
0
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
77
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
0
0
0
16
0
% R
% Ser:
0
0
39
0
54
0
0
0
0
0
0
0
16
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
77
8
0
0
0
0
62
% T
% Val:
62
0
0
0
8
62
70
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
77
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _