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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3L
All Species:
28.18
Human Site:
Y278
Identified Species:
51.67
UniProt:
Q5TA45
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TA45
NP_060341.2
600
67663
Y278
L
T
E
K
A
N
H
Y
Y
K
L
F
I
P
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092173
518
58516
A248
A
T
P
G
M
L
H
A
G
Q
S
L
Q
I
F
Dog
Lupus familis
XP_536711
600
67738
Y278
L
T
E
K
A
N
H
Y
Y
K
L
F
I
T
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWS4
600
67825
Y278
L
T
E
K
A
N
H
Y
Y
K
L
F
I
T
W
Rat
Rattus norvegicus
Q3MHC2
600
67822
Y278
L
T
E
K
A
N
H
Y
Y
K
L
F
I
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIH0
600
68170
Y278
L
T
E
K
A
N
H
Y
Y
K
L
F
I
T
W
Frog
Xenopus laevis
Q9W799
783
88968
F279
V
S
Y
N
V
V
E
F
S
K
S
Q
V
E
W
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
Y278
L
T
E
K
A
N
H
Y
Y
K
L
F
I
T
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
F279
V
S
Y
N
V
I
E
F
A
K
S
Q
I
E
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495706
608
68677
Y283
L
A
E
R
A
N
Q
Y
Y
R
L
F
I
S
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GUU3
613
67986
Y277
L
T
I
Q
A
N
M
Y
Y
K
M
L
I
S
W
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
V289
L
A
K
K
C
M
S
V
F
Q
T
Y
V
N
M
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
V297
L
A
R
K
C
M
L
V
Y
Q
T
Y
V
G
S
Conservation
Percent
Protein Identity:
100
N.A.
85.6
97.5
N.A.
97.1
97
N.A.
N.A.
92
23.8
84
N.A.
23.6
N.A.
55.2
N.A.
Protein Similarity:
100
N.A.
86.1
98.5
N.A.
98.6
98.6
N.A.
N.A.
95.8
41.2
92.6
N.A.
42.7
N.A.
72.5
N.A.
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
13.3
93.3
N.A.
20
N.A.
66.6
N.A.
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
40
93.3
N.A.
40
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
28.7
24.8
Protein Similarity:
N.A.
N.A.
N.A.
65.5
47.1
40.5
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
0
62
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
54
0
0
0
16
0
0
0
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
16
8
0
0
54
0
0
8
% F
% Gly:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
0
0
70
8
0
% I
% Lys:
0
0
8
62
0
0
0
0
0
70
0
0
0
0
0
% K
% Leu:
77
0
0
0
0
8
8
0
0
0
54
16
0
0
0
% L
% Met:
0
0
0
0
8
16
8
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
16
0
62
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
24
0
16
8
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
16
0
0
0
0
8
0
8
0
24
0
0
16
8
% S
% Thr:
0
62
0
0
0
0
0
0
0
0
16
0
0
39
0
% T
% Val:
16
0
0
0
16
8
0
16
0
0
0
0
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% W
% Tyr:
0
0
16
0
0
0
0
62
70
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _