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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF3L
All Species:
22.73
Human Site:
Y578
Identified Species:
41.67
UniProt:
Q5TA45
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TA45
NP_060341.2
600
67663
Y578
V
L
L
V
S
W
T
Y
Q
D
E
E
L
G
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092173
518
58516
Y496
V
L
L
V
S
W
T
Y
Q
D
E
E
L
G
S
Dog
Lupus familis
XP_536711
600
67738
Y578
V
L
L
V
S
W
T
Y
Q
D
E
E
L
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWS4
600
67825
Y578
V
L
L
V
S
W
T
Y
Q
D
E
E
L
G
S
Rat
Rattus norvegicus
Q3MHC2
600
67822
Y578
V
L
L
V
S
W
T
Y
Q
D
E
E
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIH0
600
68170
Y578
V
L
L
V
S
W
T
Y
Q
D
E
E
L
G
S
Frog
Xenopus laevis
Q9W799
783
88968
V749
V
L
V
C
N
N
M
V
A
V
R
R
T
E
T
Zebra Danio
Brachydanio rerio
Q503E1
598
67573
W577
L
K
V
I
L
L
S
W
S
Y
Q
D
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
L722
L
W
C
S
N
G
T
L
A
L
R
R
V
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495706
608
68677
Q580
I
W
D
E
C
R
E
Q
W
F
K
V
I
H
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GUU3
613
67986
E586
R
S
S
S
S
S
S
E
A
V
F
L
C
C
N
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
C678
V
K
L
S
S
H
S
C
D
D
H
D
H
N
N
Red Bread Mold
Neurospora crassa
Q8WZS6
850
94060
N661
V
E
L
E
W
E
G
N
M
L
N
D
G
I
A
Conservation
Percent
Protein Identity:
100
N.A.
85.6
97.5
N.A.
97.1
97
N.A.
N.A.
92
23.8
84
N.A.
23.6
N.A.
55.2
N.A.
Protein Similarity:
100
N.A.
86.1
98.5
N.A.
98.6
98.6
N.A.
N.A.
95.8
41.2
92.6
N.A.
42.7
N.A.
72.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
33.3
46.6
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
28.7
24.8
Protein Similarity:
N.A.
N.A.
N.A.
65.5
47.1
40.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
16
% A
% Cys:
0
0
8
8
8
0
0
8
0
0
0
0
8
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
54
0
24
0
8
0
% D
% Glu:
0
8
0
16
0
8
8
8
0
0
47
47
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
0
0
8
47
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
8
0
8
8
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
16
0
0
0
0
0
0
0
0
8
0
0
0
8
% K
% Leu:
16
54
62
0
8
8
0
8
0
16
0
8
47
0
8
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
8
0
8
0
0
8
0
0
8
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
47
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
0
8
0
0
0
0
16
16
0
0
0
% R
% Ser:
0
8
8
24
62
8
24
0
8
0
0
0
0
0
47
% S
% Thr:
0
0
0
0
0
0
54
0
0
0
0
0
8
0
8
% T
% Val:
70
0
16
47
0
0
0
8
0
16
0
8
8
0
0
% V
% Trp:
0
16
0
0
8
47
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _