KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES5
All Species:
20
Human Site:
T5
Identified Species:
55
UniProt:
Q5TA89
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TA89
NP_001010926.1
166
18226
T5
_
_
_
M
A
P
S
T
V
A
V
E
L
L
S
Chimpanzee
Pan troglodytes
XP_524847
165
18136
T5
_
_
_
M
A
P
S
T
V
A
V
E
L
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546734
165
18420
T5
_
_
_
M
A
P
S
T
V
A
V
E
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P70120
167
18407
T5
_
_
_
M
A
P
S
T
V
A
V
E
M
L
S
Rat
Rattus norvegicus
Q03062
166
18434
T5
_
_
_
M
A
P
S
T
V
A
V
E
M
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510401
81
9507
Chicken
Gallus gallus
O57337
290
31053
S21
P
I
A
G
A
P
A
S
A
S
H
T
P
D
K
Frog
Xenopus laevis
Q90VV1
277
29807
N20
P
I
A
G
A
P
A
N
S
A
Q
T
P
D
K
Zebra Danio
Brachydanio rerio
Q8AXV6
317
33920
N32
A
D
E
N
A
G
A
N
S
P
L
G
S
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
89.7
N.A.
92.8
89.1
N.A.
37.3
26.5
27
24.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
90.9
N.A.
94.6
91.5
N.A.
42.1
37.2
38.6
35.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
91.6
91.6
N.A.
0
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
40
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
0
89
0
34
0
12
67
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
0
0
23
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
56
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
23
0
12
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
12
0
34
56
0
% L
% Met:
0
0
0
56
0
0
0
0
0
0
0
0
23
12
0
% M
% Asn:
0
0
0
12
0
0
0
23
0
0
0
0
0
0
0
% N
% Pro:
23
0
0
0
0
78
0
0
0
12
0
0
23
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
56
12
23
12
0
0
12
0
67
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
0
23
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
56
0
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
56
56
56
0
0
0
0
0
0
0
0
0
0
0
0
% _