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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HES5 All Species: 22.42
Human Site: Y88 Identified Species: 61.67
UniProt: Q5TA89 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TA89 NP_001010926.1 166 18226 Y88 P K S L H Q D Y S E G Y S W C
Chimpanzee Pan troglodytes XP_524847 165 18136 Y88 P K S L H Q D Y S E G Y S W C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546734 165 18420 Y88 P K S L H Q D Y S E G Y S W C
Cat Felis silvestris
Mouse Mus musculus P70120 167 18407 Y88 P K S L H Q D Y S E G Y S W C
Rat Rattus norvegicus Q03062 166 18434 Y88 P K S L H Q D Y S E G Y S W C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510401 81 9507 V26 K N K L R K P V V E K M R R D
Chicken Gallus gallus O57337 290 31053 Y111 D P S V L G K Y R A G F N E C
Frog Xenopus laevis Q90VV1 277 29807 Y110 D P S V L G K Y R A G F N E C
Zebra Danio Brachydanio rerio Q8AXV6 317 33920 M119 F D A H A L A M D Y R G L G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 89.7 N.A. 92.8 89.1 N.A. 37.3 26.5 27 24.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 N.A. 90.9 N.A. 94.6 91.5 N.A. 42.1 37.2 38.6 35.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 13.3 26.6 26.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 46.6 46.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 0 12 0 0 23 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % C
% Asp: 23 12 0 0 0 0 56 0 12 0 0 0 0 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 67 0 0 0 23 0 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 0 23 0 0 12 % F
% Gly: 0 0 0 0 0 23 0 0 0 0 78 12 0 12 0 % G
% His: 0 0 0 12 56 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 56 12 0 0 12 23 0 0 0 12 0 0 0 0 % K
% Leu: 0 0 0 67 23 12 0 0 0 0 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 12 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 0 23 0 0 % N
% Pro: 56 23 0 0 0 0 12 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 56 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 12 0 0 0 23 0 12 0 12 12 0 % R
% Ser: 0 0 78 0 0 0 0 0 56 0 0 0 56 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 23 0 0 0 12 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 56 0 % W
% Tyr: 0 0 0 0 0 0 0 78 0 12 0 56 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _