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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC1A
All Species:
16.97
Human Site:
S422
Identified Species:
41.48
UniProt:
Q5TB30
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TB30
NP_001107592.1
784
89358
S422
N
S
K
P
R
C
C
S
L
E
G
I
V
D
V
Chimpanzee
Pan troglodytes
XP_001165122
784
89401
S422
N
S
K
P
R
C
C
S
L
E
G
I
V
D
V
Rhesus Macaque
Macaca mulatta
XP_001096281
784
89056
S422
N
N
K
P
R
C
C
S
L
E
G
I
V
D
V
Dog
Lupus familis
XP_537116
857
98077
Y467
S
N
I
K
P
R
C
Y
S
L
E
G
I
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG0
804
92183
S423
N
I
K
P
R
C
S
S
L
E
G
I
V
D
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512859
866
98552
L474
F
R
P
R
C
Y
S
L
E
G
I
A
D
S
P
Chicken
Gallus gallus
Q5ZLD2
529
61095
V197
T
L
A
R
L
Q
K
V
L
G
L
D
C
L
D
Frog
Xenopus laevis
Q6ING4
806
92590
E414
N
L
S
T
S
R
K
E
T
G
V
T
R
K
V
Zebra Danio
Brachydanio rerio
Q803Q4
800
90672
S412
R
L
R
P
R
S
C
S
L
E
G
N
I
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183893
1279
143476
G550
P
T
R
P
K
S
G
G
L
F
A
S
K
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
72.5
N.A.
74.1
N.A.
N.A.
58.3
30.3
48.5
44.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.6
97.9
80.5
N.A.
82
N.A.
N.A.
69.9
43.6
64.8
64.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
93.3
6.6
N.A.
80
N.A.
N.A.
0
6.6
13.3
46.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
80
N.A.
N.A.
0
6.6
13.3
66.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
10
40
50
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
10
40
20
% D
% Glu:
0
0
0
0
0
0
0
10
10
50
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
10
10
0
30
50
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
10
40
20
0
0
% I
% Lys:
0
0
40
10
10
0
20
0
0
0
0
0
10
10
0
% K
% Leu:
0
30
0
0
10
0
0
10
70
10
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
20
0
0
0
0
0
0
0
0
0
10
0
10
10
% N
% Pro:
10
0
10
60
10
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
20
20
50
20
0
0
0
0
0
0
10
10
10
% R
% Ser:
10
20
10
0
10
20
20
50
10
0
0
10
0
10
0
% S
% Thr:
10
10
0
10
0
0
0
0
10
0
0
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
0
40
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _