KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC1A
All Species:
29.7
Human Site:
Y699
Identified Species:
72.59
UniProt:
Q5TB30
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TB30
NP_001107592.1
784
89358
Y699
A
V
E
K
H
L
D
Y
L
K
K
G
H
V
S
Chimpanzee
Pan troglodytes
XP_001165122
784
89401
Y699
A
V
E
K
H
L
D
Y
L
K
K
G
H
V
S
Rhesus Macaque
Macaca mulatta
XP_001096281
784
89056
Y699
A
V
E
K
H
L
D
Y
L
K
K
G
H
V
S
Dog
Lupus familis
XP_537116
857
98077
Y744
A
V
D
K
H
L
D
Y
L
R
K
G
Y
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG0
804
92183
Y693
A
V
E
K
H
L
D
Y
I
K
K
G
N
V
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512859
866
98552
Y753
A
V
E
T
H
L
D
Y
L
K
K
G
Q
I
Q
Chicken
Gallus gallus
Q5ZLD2
529
61095
A445
D
E
F
E
Y
Q
R
A
T
G
S
Q
E
P
L
Frog
Xenopus laevis
Q6ING4
806
92590
Y699
A
V
Q
D
H
V
Q
Y
L
Q
R
P
R
V
K
Zebra Danio
Brachydanio rerio
Q803Q4
800
90672
Y689
A
V
E
D
H
I
N
Y
L
K
S
L
S
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183893
1279
143476
Y827
D
I
E
E
R
L
T
Y
L
K
R
S
Q
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
72.5
N.A.
74.1
N.A.
N.A.
58.3
30.3
48.5
44.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.6
97.9
80.5
N.A.
82
N.A.
N.A.
69.9
43.6
64.8
64.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
100
66.6
N.A.
80
N.A.
N.A.
73.3
0
40
46.6
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
80
13.3
66.6
60
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
20
0
10
20
0
0
60
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
70
20
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
60
0
0
0
% G
% His:
0
0
0
0
80
0
0
0
0
0
0
0
30
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
10
0
0
0
0
30
0
% I
% Lys:
0
0
0
50
0
0
0
0
0
70
60
0
0
0
40
% K
% Leu:
0
0
0
0
0
70
0
0
80
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
10
0
0
10
10
0
0
10
0
10
20
0
10
% Q
% Arg:
0
0
0
0
10
0
10
0
0
10
20
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
20
10
10
10
30
% S
% Thr:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% T
% Val:
0
80
0
0
0
10
0
0
0
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
90
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _