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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1009 All Species: 7.27
Human Site: S422 Identified Species: 22.86
UniProt: Q5TB80 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TB80 NP_055710.2 1403 161943 S422 L Q K T T N E S M E N S C P Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086275 1325 152531 S434 L Y A S V R S S G Y G K P S S
Dog Lupus familis XP_532220 1405 161885 T417 N V V L K K T T N K D I E N S
Cat Felis silvestris
Mouse Mus musculus Q6ZQ06 1403 160836 T434 M G S S C P A T E E H L D K M
Rat Rattus norvegicus Q4KLH6 1403 160982 G422 L H R T A G E G V G S S C P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512972 1476 168159 S491 G N E A S E E S S Q R V T V E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122694 1389 160451 F481 L T P R L E L F A D A I P K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 S167 L Y I N E I K S L K H E I K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90.7 84.2 N.A. 75.5 74.9 N.A. 58.4 N.A. N.A. N.A. N.A. N.A. 20.1 N.A. N.A.
Protein Similarity: 100 N.A. 92.5 92.7 N.A. 86.4 86.1 N.A. 74.2 N.A. N.A. N.A. N.A. N.A. 41.7 N.A. N.A.
P-Site Identity: 100 N.A. 13.3 0 N.A. 6.6 40 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 20 20 N.A. 33.3 60 N.A. 40 N.A. N.A. N.A. N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 13 13 0 13 0 13 0 13 0 0 0 13 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 0 0 25 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 13 13 0 13 0 0 % D
% Glu: 0 0 13 0 13 25 38 0 13 25 0 13 13 0 25 % E
% Phe: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % F
% Gly: 13 13 0 0 0 13 0 13 13 13 13 0 0 0 0 % G
% His: 0 13 0 0 0 0 0 0 0 0 25 0 0 0 0 % H
% Ile: 0 0 13 0 0 13 0 0 0 0 0 25 13 0 0 % I
% Lys: 0 0 13 0 13 13 13 0 0 25 0 13 0 38 0 % K
% Leu: 63 0 0 13 13 0 13 0 13 0 0 13 0 0 13 % L
% Met: 13 0 0 0 0 0 0 0 13 0 0 0 0 0 13 % M
% Asn: 13 13 0 13 0 13 0 0 13 0 13 0 0 13 0 % N
% Pro: 0 0 13 0 0 13 0 0 0 0 0 0 25 25 0 % P
% Gln: 0 13 0 0 0 0 0 0 0 13 0 0 0 0 13 % Q
% Arg: 0 0 13 13 0 13 0 0 0 0 13 0 0 0 0 % R
% Ser: 0 0 13 25 13 0 13 50 13 0 13 25 0 13 25 % S
% Thr: 0 13 0 25 13 0 13 25 0 0 0 0 13 0 0 % T
% Val: 0 13 13 0 13 0 0 0 13 0 0 13 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 25 0 0 0 0 0 0 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _