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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRY All Species: 11.52
Human Site: S2575 Identified Species: 36.19
UniProt: Q5TBA9 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TBA9 NP_075463.2 3013 338875 S2575 S F N T R M S S F D A S L P D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534510 3011 338468 S2573 S F N T R M A S F D A S L S D
Cat Felis silvestris
Mouse Mus musculus NP_766475 3020 339074 N2582 S F N T R M A N F E A S L P D
Rat Rattus norvegicus NP_001163869 3011 338356 N2573 P F N A R I T N F E A S L P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509448 3011 338588 S2573 S F N A R T S S F D V A L P A
Chicken Gallus gallus
Frog Xenopus laevis NP_001104227 3010 338907 S2573 S L N T R T S S F D A S L P E
Zebra Danio Brachydanio rerio XP_001332249 3010 337949 C2572 S L N A A T P C L G T S L P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VT28 3479 384333 F2996 K G G H S S A F E D S F S D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.6 N.A. 96.5 95.7 N.A. 94.1 N.A. 88.3 78.4 N.A. 34.7 N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 98.8 N.A. 98.4 98 N.A. 96.9 N.A. 94.9 88.3 N.A. 52.3 N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 80 60 N.A. 66.6 N.A. 80 40 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 100 86.6 N.A. 73.3 N.A. 86.6 40 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 38 13 0 38 0 0 0 63 13 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 63 0 0 0 13 63 % D
% Glu: 0 0 0 0 0 0 0 0 13 25 0 0 0 0 13 % E
% Phe: 0 63 0 0 0 0 0 13 75 0 0 13 0 0 0 % F
% Gly: 0 13 13 0 0 0 0 0 0 13 0 0 0 0 0 % G
% His: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 25 0 0 0 0 0 0 13 0 0 0 88 0 0 % L
% Met: 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 88 0 0 0 0 25 0 0 0 0 0 0 0 % N
% Pro: 13 0 0 0 0 0 13 0 0 0 0 0 0 75 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 75 0 0 0 13 13 38 50 0 0 13 75 13 13 0 % S
% Thr: 0 0 0 50 0 38 13 0 0 0 13 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _