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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2B
All Species:
28.79
Human Site:
S229
Identified Species:
63.33
UniProt:
Q5TBB1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TBB1
NP_078846.2
312
35139
S229
K
E
L
S
D
D
L
S
K
Y
L
K
L
P
E
Chimpanzee
Pan troglodytes
XP_001158221
315
35573
S229
K
E
L
S
D
D
L
S
K
Y
L
K
L
P
E
Rhesus Macaque
Macaca mulatta
XP_001105134
312
35124
S229
K
E
L
S
D
D
L
S
K
Y
L
K
L
P
E
Dog
Lupus familis
XP_848995
279
31902
A196
K
E
L
S
D
D
L
A
K
Y
L
K
L
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZV0
308
34711
S226
K
E
L
S
D
D
L
S
K
F
L
K
L
P
E
Rat
Rattus norvegicus
Q5XI96
307
34554
S225
K
E
L
S
D
D
L
S
K
L
L
K
L
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513581
307
34792
S227
K
D
L
S
E
D
L
S
K
H
L
Q
L
P
E
Chicken
Gallus gallus
NP_001025997
254
29052
K177
N
Q
T
V
K
A
L
K
S
N
N
I
C
V
G
Frog
Xenopus laevis
Q5HZP1
306
34225
S227
E
D
L
R
E
D
L
S
K
Y
L
G
L
P
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572908
340
37578
T239
A
D
L
H
G
L
L
T
S
Y
L
H
I
P
S
Honey Bee
Apis mellifera
XP_395945
307
34937
A227
E
D
L
S
K
K
L
A
Q
Y
L
N
I
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
97.1
76.9
N.A.
80.7
80.4
N.A.
63.4
47.7
54.1
N.A.
N.A.
25
29.4
N.A.
N.A.
Protein Similarity:
100
98.4
97.7
83.9
N.A.
88.1
88.4
N.A.
75.3
58.9
68.5
N.A.
N.A.
40.5
51.9
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
73.3
6.6
60
N.A.
N.A.
33.3
40
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
13.3
86.6
N.A.
N.A.
53.3
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
37
0
0
55
73
0
0
0
0
0
0
0
0
19
% D
% Glu:
19
55
0
0
19
0
0
0
0
0
0
0
0
0
64
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% I
% Lys:
64
0
0
0
19
10
0
10
73
0
0
55
0
0
0
% K
% Leu:
0
0
91
0
0
10
100
0
0
10
91
0
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
73
0
0
0
64
19
0
0
0
0
0
10
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _