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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2A
All Species:
12.42
Human Site:
S547
Identified Species:
30.37
UniProt:
Q5TCZ1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCZ1
NP_055446.2
1133
125289
S547
G
A
S
E
S
Q
D
S
P
R
K
L
K
Y
E
Chimpanzee
Pan troglodytes
XP_508015
1105
121746
S519
G
A
S
E
S
Q
D
S
P
R
K
L
K
Y
E
Rhesus Macaque
Macaca mulatta
XP_001113943
1074
118123
A498
R
P
K
V
P
P
P
A
P
P
S
K
P
K
E
Dog
Lupus familis
XP_544004
1141
125129
S557
G
S
T
E
S
Q
D
S
P
L
K
L
K
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
O89032
1124
124153
S546
G
A
C
E
S
Q
G
S
P
L
K
V
K
Y
E
Rat
Rattus norvegicus
NP_001101076
1073
118192
L497
C
E
N
Q
G
S
P
L
K
L
K
Y
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512205
1081
119576
P505
S
Q
D
A
L
P
K
P
R
Y
E
E
P
E
Y
Chicken
Gallus gallus
XP_421741
1108
124935
P522
R
T
S
T
L
T
R
P
K
V
P
P
P
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
K527
P
P
P
A
P
P
V
K
K
Q
D
S
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
R42
G
S
V
N
V
V
Y
R
R
Y
S
T
F
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
90.1
90.2
N.A.
91
87.1
N.A.
75.2
74.9
N.A.
58.3
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
97.2
90.6
92.6
N.A.
93.7
89.5
N.A.
81.9
82.9
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
13.3
80
N.A.
73.3
6.6
N.A.
0
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
80
26.6
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
20
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
30
0
0
0
10
0
0
0
10
% D
% Glu:
0
10
0
40
0
0
0
0
0
0
10
10
20
30
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% F
% Gly:
50
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
10
30
0
50
10
40
10
0
% K
% Leu:
0
0
0
0
20
0
0
10
0
30
0
30
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
20
10
0
20
30
20
20
50
10
10
10
30
0
20
% P
% Gln:
0
10
0
10
0
40
0
0
0
10
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
0
10
10
20
20
0
0
0
0
0
% R
% Ser:
10
20
30
0
40
10
0
40
0
0
20
10
0
0
0
% S
% Thr:
0
10
10
10
0
10
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
10
10
10
10
10
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
20
0
10
0
40
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _