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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2A
All Species:
14.85
Human Site:
S634
Identified Species:
36.3
UniProt:
Q5TCZ1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCZ1
NP_055446.2
1133
125289
S634
P
Y
A
E
D
T
L
S
A
R
G
S
S
G
D
Chimpanzee
Pan troglodytes
XP_508015
1105
121746
S606
P
Y
A
E
D
T
L
S
A
R
G
S
S
G
D
Rhesus Macaque
Macaca mulatta
XP_001113943
1074
118123
A585
G
E
S
S
E
D
V
A
L
E
E
E
T
I
Y
Dog
Lupus familis
XP_544004
1141
125129
S644
P
C
A
E
D
T
L
S
A
R
R
S
S
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O89032
1124
124153
S633
P
Y
T
E
D
T
L
S
A
R
G
S
S
G
D
Rat
Rattus norvegicus
NP_001101076
1073
118192
R584
T
E
D
T
L
S
A
R
G
S
S
G
D
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512205
1081
119576
D592
R
E
S
S
G
D
S
D
S
Q
K
S
T
S
L
Chicken
Gallus gallus
XP_421741
1108
124935
V609
L
Q
K
A
K
F
K
V
G
E
S
S
E
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
T614
S
P
L
L
K
V
M
T
S
P
L
R
K
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
S129
T
P
T
P
E
D
V
S
P
P
S
P
D
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
90.1
90.2
N.A.
91
87.1
N.A.
75.2
74.9
N.A.
58.3
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
97.2
90.6
92.6
N.A.
93.7
89.5
N.A.
81.9
82.9
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
0
80
N.A.
93.3
6.6
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
33.3
80
N.A.
93.3
13.3
N.A.
33.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
10
0
0
10
10
40
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
40
30
0
10
0
0
0
0
20
10
50
% D
% Glu:
0
30
0
40
20
0
0
0
0
20
10
10
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
20
0
30
10
0
40
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
0
20
0
10
0
0
0
10
0
10
0
0
% K
% Leu:
10
0
10
10
10
0
40
0
10
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
40
20
0
10
0
0
0
0
10
20
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
40
10
10
0
20
0
% R
% Ser:
10
0
20
20
0
10
10
50
20
10
30
60
40
20
0
% S
% Thr:
20
0
20
10
0
40
0
10
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
10
20
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _