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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2A
All Species:
8.48
Human Site:
S755
Identified Species:
20.74
UniProt:
Q5TCZ1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCZ1
NP_055446.2
1133
125289
S755
S
C
P
R
A
K
P
S
V
R
P
K
P
F
L
Chimpanzee
Pan troglodytes
XP_508015
1105
121746
S727
S
C
A
R
A
K
P
S
V
R
P
K
P
F
L
Rhesus Macaque
Macaca mulatta
XP_001113943
1074
118123
R701
S
A
S
D
A
G
I
R
G
T
P
K
V
R
A
Dog
Lupus familis
XP_544004
1141
125129
S763
S
C
A
R
A
K
P
S
V
R
P
K
P
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O89032
1124
124153
A749
G
L
A
S
C
A
R
A
K
P
S
V
R
P
K
Rat
Rattus norvegicus
NP_001101076
1073
118192
P700
A
S
C
V
R
A
K
P
S
V
R
P
K
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512205
1081
119576
E708
K
P
F
L
S
K
G
E
S
Q
S
Q
E
K
M
Chicken
Gallus gallus
XP_421741
1108
124935
K732
A
K
P
I
V
R
P
K
P
F
L
N
K
A
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
V731
P
L
A
R
P
K
P
V
V
R
P
K
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
F245
Q
A
E
D
E
I
S
F
E
T
G
V
V
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
90.1
90.2
N.A.
91
87.1
N.A.
75.2
74.9
N.A.
58.3
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
97.2
90.6
92.6
N.A.
93.7
89.5
N.A.
81.9
82.9
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
93.3
26.6
93.3
N.A.
0
0
N.A.
6.6
13.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
26.6
93.3
N.A.
6.6
13.3
N.A.
33.3
26.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
40
0
40
20
0
10
0
0
0
0
0
10
10
% A
% Cys:
0
30
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
10
0
0
10
10
0
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
10
0
10
0
0
0
30
0
% F
% Gly:
10
0
0
0
0
10
10
0
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
0
50
10
10
10
0
0
50
20
10
10
% K
% Leu:
0
20
0
10
0
0
0
0
0
0
10
0
0
10
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
10
20
0
10
0
50
10
10
10
50
10
40
20
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
0
40
10
10
10
10
0
40
10
0
10
10
0
% R
% Ser:
40
10
10
10
10
0
10
30
20
0
20
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
10
% T
% Val:
0
0
0
10
10
0
0
10
40
10
0
20
20
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _