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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2A
All Species:
7.58
Human Site:
T157
Identified Species:
18.52
UniProt:
Q5TCZ1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCZ1
NP_055446.2
1133
125289
T157
E
S
P
K
K
D
V
T
G
A
D
A
T
A
E
Chimpanzee
Pan troglodytes
XP_508015
1105
121746
N129
E
A
R
P
E
D
V
N
P
P
K
E
D
V
G
Rhesus Macaque
Macaca mulatta
XP_001113943
1074
118123
D115
P
P
H
I
S
Q
C
D
E
V
F
R
F
F
E
Dog
Lupus familis
XP_544004
1141
125129
T167
E
S
P
K
K
D
A
T
G
A
D
T
N
A
E
Cat
Felis silvestris
Mouse
Mus musculus
O89032
1124
124153
T157
E
S
P
K
K
D
V
T
G
A
D
T
N
A
E
Rat
Rattus norvegicus
NP_001101076
1073
118192
P114
G
A
D
T
N
A
E
P
M
I
L
E
Q
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512205
1081
119576
K122
K
E
D
Y
G
S
T
K
R
K
S
V
W
M
S
Chicken
Gallus gallus
XP_421741
1108
124935
A134
P
I
D
E
Y
C
R
A
L
V
R
L
P
P
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
K140
E
D
Y
G
S
K
R
K
S
G
L
D
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
90.1
90.2
N.A.
91
87.1
N.A.
75.2
74.9
N.A.
58.3
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
97.2
90.6
92.6
N.A.
93.7
89.5
N.A.
81.9
82.9
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
20
6.6
80
N.A.
86.6
0
N.A.
0
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
6.6
80
N.A.
86.6
6.6
N.A.
6.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
10
10
10
0
30
0
10
0
30
0
% A
% Cys:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
30
0
0
40
0
10
0
0
30
10
10
0
0
% D
% Glu:
50
10
0
10
10
0
10
0
10
0
0
20
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% F
% Gly:
10
0
0
10
10
0
0
0
30
10
0
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
30
30
10
0
20
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
20
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
20
0
0
% N
% Pro:
20
10
30
10
0
0
0
10
10
10
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
20
0
10
0
10
10
0
0
0
% R
% Ser:
0
30
0
0
20
10
0
0
10
0
10
0
10
10
10
% S
% Thr:
0
0
0
10
0
0
10
30
0
0
0
20
10
0
0
% T
% Val:
0
0
0
0
0
0
30
0
0
20
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
10
10
10
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _