KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2A
All Species:
12.73
Human Site:
Y553
Identified Species:
31.11
UniProt:
Q5TCZ1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCZ1
NP_055446.2
1133
125289
Y553
D
S
P
R
K
L
K
Y
E
E
P
E
Y
D
I
Chimpanzee
Pan troglodytes
XP_508015
1105
121746
Y525
D
S
P
R
K
L
K
Y
E
E
P
E
Y
D
I
Rhesus Macaque
Macaca mulatta
XP_001113943
1074
118123
K504
P
A
P
P
S
K
P
K
E
A
E
E
G
P
T
Dog
Lupus familis
XP_544004
1141
125129
Y563
D
S
P
L
K
L
K
Y
E
E
P
E
Y
D
I
Cat
Felis silvestris
Mouse
Mus musculus
O89032
1124
124153
Y552
G
S
P
L
K
V
K
Y
E
E
P
E
Y
D
V
Rat
Rattus norvegicus
NP_001101076
1073
118192
E503
P
L
K
L
K
Y
E
E
P
E
Y
D
I
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512205
1081
119576
E511
K
P
R
Y
E
E
P
E
Y
D
I
P
A
F
G
Chicken
Gallus gallus
XP_421741
1108
124935
A528
R
P
K
V
P
P
P
A
P
P
S
K
P
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
E533
V
K
K
Q
D
S
E
E
G
P
S
L
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
F48
Y
R
R
Y
S
T
F
F
D
F
Q
N
K
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
90.1
90.2
N.A.
91
87.1
N.A.
75.2
74.9
N.A.
58.3
N.A.
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
97.2
90.6
92.6
N.A.
93.7
89.5
N.A.
81.9
82.9
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
20
93.3
N.A.
73.3
13.3
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
86.6
26.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
0
0
10
0
0
0
10
10
0
10
0
40
10
% D
% Glu:
0
0
0
0
10
10
20
30
50
50
10
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
10
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
10
0
0
0
20
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
30
% I
% Lys:
10
10
30
0
50
10
40
10
0
0
0
10
10
10
0
% K
% Leu:
0
10
0
30
0
30
0
0
0
0
0
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
20
20
50
10
10
10
30
0
20
20
40
10
10
20
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
10
20
20
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
40
0
0
20
10
0
0
0
0
20
0
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
20
0
10
0
40
10
0
10
0
40
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _