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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPH4A
All Species:
12.12
Human Site:
S223
Identified Species:
29.63
UniProt:
Q5TD94
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TD94
NP_001010892.1
716
80733
S223
A
Y
L
L
K
T
S
S
N
S
G
F
N
L
Y
Chimpanzee
Pan troglodytes
XP_001162376
715
80526
S223
A
Y
L
L
K
T
S
S
N
S
G
F
N
L
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541210
717
80508
S221
A
Y
L
L
K
T
S
S
K
S
G
L
N
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYM7
716
80128
S222
A
Y
L
L
S
T
S
S
K
S
G
L
N
L
Y
Rat
Rattus norvegicus
NP_001019919
650
73152
N220
N
L
L
T
K
I
L
N
Q
R
P
E
D
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518144
452
51703
A39
P
L
P
N
I
M
E
A
A
F
Y
F
E
Q
A
Chicken
Gallus gallus
XP_420671
648
72693
E220
F
K
S
D
A
G
D
E
E
R
E
E
E
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923773
537
59934
F124
N
V
A
E
L
A
F
F
F
E
Q
A
G
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624190
561
64759
L147
F
E
Q
T
G
I
G
L
P
R
R
E
L
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999761
552
62705
E139
E
H
D
G
G
E
D
E
V
E
T
P
L
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
79.9
N.A.
74.3
46.7
N.A.
47
54.6
N.A.
38.4
N.A.
N.A.
30
N.A.
48.6
Protein Similarity:
100
99.7
N.A.
86
N.A.
82.1
62.4
N.A.
53
66
N.A.
52
N.A.
N.A.
48
N.A.
61
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
13.3
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
80
26.6
N.A.
13.3
6.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
10
0
10
10
0
10
10
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
20
0
0
0
0
0
10
0
0
% D
% Glu:
10
10
0
10
0
10
10
20
10
20
10
30
20
0
0
% E
% Phe:
20
0
0
0
0
0
10
10
10
10
0
30
0
0
0
% F
% Gly:
0
0
0
10
20
10
10
0
0
0
40
0
10
0
20
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
40
0
0
0
20
0
0
0
0
0
0
% K
% Leu:
0
20
50
40
10
0
10
10
0
0
0
20
20
50
20
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
10
0
0
0
10
20
0
0
0
40
0
10
% N
% Pro:
10
0
10
0
0
0
0
0
10
0
10
10
0
20
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
30
10
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
40
40
0
40
0
0
0
0
0
% S
% Thr:
0
0
0
20
0
40
0
0
0
0
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
10
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
40
0
0
0
0
0
0
0
0
10
0
0
0
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _