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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDI2
All Species:
18.79
Human Site:
S45
Identified Species:
34.44
UniProt:
Q5TDH0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TDH0
NP_115717.3
399
44523
S45
S
G
I
P
A
A
E
S
Q
I
V
Y
A
E
R
Chimpanzee
Pan troglodytes
XP_001154591
392
43542
I45
S
R
V
P
V
E
E
I
Q
I
I
H
M
E
R
Rhesus Macaque
Macaca mulatta
XP_001083343
399
44446
S45
S
G
I
P
A
A
E
S
Q
I
V
Y
A
E
R
Dog
Lupus familis
XP_544554
399
44459
I45
S
G
I
P
A
A
E
I
Q
I
V
Y
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
A2ADY9
399
44572
S45
S
G
I
P
A
A
E
S
Q
I
V
Y
A
E
R
Rat
Rattus norvegicus
A0JPP7
408
45432
A45
S
G
V
P
A
E
E
A
Q
I
V
Y
M
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511851
386
43141
S45
D
N
H
R
S
L
A
S
Y
G
L
K
D
G
D
Chicken
Gallus gallus
XP_423293
358
40255
S45
S
G
I
P
A
A
E
S
Q
I
V
Y
A
E
R
Frog
Xenopus laevis
Q7ZYA7
393
43714
T45
S
G
I
P
A
S
D
T
L
I
V
Y
A
E
R
Zebra Danio
Brachydanio rerio
Q6TH22
411
45578
I45
S
G
I
P
A
G
E
I
Q
I
I
Y
A
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573129
458
50519
I41
I
G
A
E
V
S
Q
I
A
V
I
F
N
G
R
Honey Bee
Apis mellifera
XP_624431
465
51996
M41
S
N
V
P
V
H
E
M
V
I
A
F
N
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S906
439
47751
Q46
T
S
H
H
P
S
T
Q
H
L
Y
H
N
G
N
Conservation
Percent
Protein Identity:
100
71.4
99.7
97.2
N.A.
95.9
72.5
N.A.
85.7
80.4
84.4
76.8
N.A.
44.9
49.2
N.A.
N.A.
Protein Similarity:
100
82.9
99.7
97.9
N.A.
97.4
83.5
N.A.
89.2
84.7
90.7
84.6
N.A.
60.9
62.3
N.A.
N.A.
P-Site Identity:
100
46.6
100
93.3
N.A.
100
66.6
N.A.
6.6
100
73.3
73.3
N.A.
13.3
26.6
N.A.
N.A.
P-Site Similarity:
100
66.6
100
93.3
N.A.
100
86.6
N.A.
20
100
93.3
86.6
N.A.
46.6
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
38.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
50.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
62
39
8
8
8
0
8
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
8
0
16
70
0
0
0
0
0
0
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% F
% Gly:
0
70
0
0
0
8
0
0
0
8
0
0
0
31
0
% G
% His:
0
0
16
8
0
8
0
0
8
0
0
16
0
0
0
% H
% Ile:
8
0
54
0
0
0
0
31
0
77
24
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
8
8
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
16
0
0
% M
% Asn:
0
16
0
0
0
0
0
0
0
0
0
0
24
0
8
% N
% Pro:
0
0
0
77
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
62
0
0
0
0
0
16
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
62
% R
% Ser:
77
8
0
0
8
24
0
39
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
0
0
24
0
24
0
0
0
8
8
54
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _