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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C6orf174
All Species:
11.52
Human Site:
S221
Identified Species:
28.15
UniProt:
Q5TF21
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TF21
NP_001012279.1
947
103199
S221
A
S
P
S
P
S
S
S
S
A
G
K
T
P
G
Chimpanzee
Pan troglodytes
XP_518732
947
103315
S221
A
S
P
S
P
S
S
S
S
A
G
K
T
P
G
Rhesus Macaque
Macaca mulatta
XP_001106088
1673
186079
S221
A
S
P
S
P
S
S
S
S
A
G
K
T
P
G
Dog
Lupus familis
XP_541235
945
102262
S228
A
P
P
S
P
S
A
S
A
G
R
A
A
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZL0
945
103461
A220
V
S
P
S
P
P
T
A
A
T
S
K
T
P
G
Rat
Rattus norvegicus
XP_002725504
944
103007
A219
V
S
P
S
P
P
T
A
A
T
S
R
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509389
760
85164
R160
P
P
P
P
K
A
W
R
G
E
G
V
V
S
K
Chicken
Gallus gallus
XP_419750
517
59383
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664826
808
91699
Q187
S
S
P
V
T
E
P
Q
R
P
P
E
D
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783370
1587
173174
N295
P
T
D
S
K
H
L
N
K
S
L
E
S
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
55.4
90.8
N.A.
91.1
90.8
N.A.
70
47.4
N.A.
60.8
N.A.
N.A.
N.A.
N.A.
21.6
Protein Similarity:
100
99.5
56
92.9
N.A.
93.5
93.3
N.A.
72.8
49.7
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
34.7
P-Site Identity:
100
100
100
40
N.A.
53.3
46.6
N.A.
13.3
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
53.3
N.A.
73.3
73.3
N.A.
20
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
10
10
20
30
30
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
10
40
0
0
10
50
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
20
0
0
0
10
0
0
40
0
0
10
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
20
20
80
10
60
20
10
0
0
10
10
0
0
50
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
10
10
0
0
10
% R
% Ser:
10
60
0
70
0
40
30
40
30
10
20
0
10
10
0
% S
% Thr:
0
10
0
0
10
0
20
0
0
20
0
0
50
10
0
% T
% Val:
20
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _