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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDGFL1
All Species:
17.17
Human Site:
S250
Identified Species:
47.22
UniProt:
Q5TGJ6
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGJ6
NP_612641.2
251
27234
S250
P
G
G
G
D
R
D
S
L
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_527245
249
27084
S248
P
G
G
G
D
R
D
S
L
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001099743
247
26948
S246
P
G
G
G
D
R
D
S
V
_
_
_
_
_
_
Dog
Lupus familis
XP_854911
230
25192
S229
P
G
I
R
D
H
E
S
L
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P51859
237
26250
S236
Q
G
V
R
D
H
E
S
L
_
_
_
_
_
_
Rat
Rattus norvegicus
Q8VHK7
237
26469
S236
Q
G
V
R
D
H
E
S
L
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5XXA9
579
64909
E566
K
T
C
G
E
E
S
E
L
E
K
P
A
K
E
Frog
Xenopus laevis
Q32N87
642
72361
Q569
K
G
P
E
D
E
N
Q
T
G
K
A
G
E
D
Zebra Danio
Brachydanio rerio
Q5XXA7
662
73469
P619
N
P
D
E
N
K
S
P
N
G
I
R
P
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
90
52.1
N.A.
55.3
55.3
N.A.
N.A.
23.3
22.4
21.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94
92.8
61.3
N.A.
63.7
64.5
N.A.
N.A.
33.3
29.7
28.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
88.8
55.5
N.A.
44.4
44.4
N.A.
N.A.
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
55.5
55.5
N.A.
N.A.
20
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
78
0
34
0
0
0
0
0
0
12
12
% D
% Glu:
0
0
0
23
12
23
34
12
0
12
0
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
78
34
45
0
0
0
0
0
23
0
0
12
0
0
% G
% His:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
23
0
0
0
0
12
0
0
0
0
23
0
0
12
0
% K
% Leu:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
12
0
12
0
12
0
0
0
0
0
0
% N
% Pro:
45
12
12
0
0
0
0
12
0
0
0
12
12
0
12
% P
% Gln:
23
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
34
0
34
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
23
67
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% T
% Val:
0
0
23
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
67
67
67
67
67
67
% _