KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO4
All Species:
16.67
Human Site:
S296
Identified Species:
40.74
UniProt:
Q5TGY1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGY1
NP_859070.3
634
67910
S296
S
G
K
Y
R
T
F
S
A
P
W
A
A
L
A
Chimpanzee
Pan troglodytes
XP_001159885
634
67850
S296
S
G
K
Y
R
T
F
S
A
P
W
A
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001094008
634
67708
S296
S
G
K
Y
R
T
F
S
A
P
W
A
A
L
A
Dog
Lupus familis
XP_544527
608
65218
S280
S
G
K
Y
R
T
F
S
A
P
W
A
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91WU4
631
67926
N293
S
G
R
Y
R
T
F
N
A
P
W
M
A
L
A
Rat
Rattus norvegicus
Q499U8
631
67776
N293
S
G
R
Y
R
T
F
N
A
P
W
M
A
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515741
592
64091
V281
M
N
G
L
V
N
I
V
A
Q
E
A
L
K
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20035
617
67324
S308
E
G
V
S
L
S
C
S
L
V
V
S
G
W
I
Sea Urchin
Strong. purpuratus
XP_782781
810
87057
T408
K
D
C
L
D
N
F
T
V
P
W
R
C
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P43564
1073
119478
L651
G
N
E
D
D
V
R
L
P
F
S
T
V
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.2
85.1
N.A.
82.3
82.6
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
36.3
Protein Similarity:
100
99.6
97.4
88.9
N.A.
88.8
88.6
N.A.
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
57.5
50.8
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
70
0
0
50
60
0
70
% A
% Cys:
0
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
0
10
20
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
70
0
0
10
0
0
0
0
0
% F
% Gly:
10
70
10
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
40
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
20
10
0
0
10
10
0
0
0
10
60
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
20
0
0
0
20
0
20
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
70
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
20
0
60
0
10
0
0
0
0
10
0
0
0
% R
% Ser:
60
0
0
10
0
10
0
50
0
0
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
60
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
10
0
10
10
0
10
10
10
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
70
0
0
10
0
% W
% Tyr:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _