KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO4
All Species:
4.85
Human Site:
S540
Identified Species:
11.85
UniProt:
Q5TGY1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGY1
NP_859070.3
634
67910
S540
L
A
P
G
C
L
P
S
E
E
P
R
Q
A
A
Chimpanzee
Pan troglodytes
XP_001159885
634
67850
S540
L
A
P
G
C
L
P
S
E
E
P
R
Q
A
A
Rhesus Macaque
Macaca mulatta
XP_001094008
634
67708
P540
L
A
P
G
C
L
P
P
E
E
P
R
Q
A
A
Dog
Lupus familis
XP_544527
608
65218
G514
K
P
G
W
D
E
K
G
L
L
L
A
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91WU4
631
67926
P536
P
L
A
P
G
S
L
P
Q
E
E
P
L
Q
T
Rat
Rattus norvegicus
Q499U8
631
67776
P536
P
L
A
P
G
G
L
P
Q
E
E
P
L
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515741
592
64091
E493
S
Q
N
G
Q
P
K
E
E
K
L
W
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20035
617
67324
Y526
N
S
K
K
I
Y
N
Y
N
L
S
H
I
V
K
Sea Urchin
Strong. purpuratus
XP_782781
810
87057
K680
A
S
D
L
L
I
P
K
S
A
S
A
M
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P43564
1073
119478
A968
P
D
E
H
E
G
I
A
R
Q
K
R
R
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.2
85.1
N.A.
82.3
82.6
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
36.3
Protein Similarity:
100
99.6
97.4
88.9
N.A.
88.8
88.6
N.A.
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
57.5
50.8
P-Site Identity:
100
100
93.3
0
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
93.3
6.6
N.A.
13.3
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
20
0
0
0
0
10
0
10
0
20
0
30
40
% A
% Cys:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
0
0
0
0
0
0
0
20
0
% D
% Glu:
0
0
10
0
10
10
0
10
40
50
20
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
40
20
20
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
10
10
0
0
20
10
0
10
10
0
0
0
10
% K
% Leu:
30
20
0
10
10
30
20
0
10
20
20
0
20
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
30
10
30
20
0
10
40
30
0
0
30
20
10
0
10
% P
% Gln:
0
10
0
0
10
0
0
0
20
10
0
0
30
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
40
10
0
0
% R
% Ser:
10
20
0
0
0
10
0
20
10
0
20
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _