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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO4
All Species:
4.55
Human Site:
T30
Identified Species:
11.11
UniProt:
Q5TGY1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGY1
NP_859070.3
634
67910
T30
E
G
E
P
H
L
P
T
G
R
E
L
T
E
A
Chimpanzee
Pan troglodytes
XP_001159885
634
67850
T30
E
G
E
P
H
L
P
T
G
R
E
L
T
E
A
Rhesus Macaque
Macaca mulatta
XP_001094008
634
67708
M30
E
G
E
P
H
L
P
M
G
R
E
L
T
E
A
Dog
Lupus familis
XP_544527
608
65218
E17
P
H
L
P
T
G
R
E
L
A
E
A
N
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91WU4
631
67926
L27
E
D
D
S
Q
Q
P
L
G
R
E
L
S
E
A
Rat
Rattus norvegicus
Q499U8
631
67776
L27
E
G
E
S
Q
Q
P
L
G
R
E
L
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515741
592
64091
Q20
R
G
L
V
K
W
L
Q
L
S
D
A
V
L
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20035
617
67324
P31
Q
P
M
S
R
G
F
P
Q
R
N
M
S
T
T
Sea Urchin
Strong. purpuratus
XP_782781
810
87057
L141
E
E
Q
L
K
K
P
L
P
E
V
L
N
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P43564
1073
119478
H326
K
S
H
K
N
L
A
H
R
L
Q
F
T
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.2
85.1
N.A.
82.3
82.6
N.A.
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
36.3
Protein Similarity:
100
99.6
97.4
88.9
N.A.
88.8
88.6
N.A.
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
57.5
50.8
P-Site Identity:
100
100
93.3
13.3
N.A.
53.3
66.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
100
93.3
13.3
N.A.
66.6
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
20
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
10
0
0
10
0
% D
% Glu:
60
10
40
0
0
0
0
10
0
10
60
0
0
50
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% F
% Gly:
0
50
0
0
0
20
0
0
50
0
0
0
0
0
0
% G
% His:
0
10
10
0
30
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
20
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
20
10
0
40
10
30
20
10
0
60
0
10
0
% L
% Met:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
10
0
20
0
0
% N
% Pro:
10
10
0
40
0
0
60
10
10
0
0
0
0
0
10
% P
% Gln:
10
0
10
0
20
20
0
10
10
0
10
0
0
10
0
% Q
% Arg:
10
0
0
0
10
0
10
0
10
60
0
0
0
10
0
% R
% Ser:
0
10
0
30
0
0
0
0
0
10
0
0
30
0
0
% S
% Thr:
0
0
0
0
10
0
0
20
0
0
0
0
40
10
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _