KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGEF3
All Species:
5.15
Human Site:
S529
Identified Species:
11.33
UniProt:
Q5TH69
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TH69
NP_065073.3
2177
240652
S529
Q
T
T
P
E
D
H
S
G
N
H
K
N
S
L
Chimpanzee
Pan troglodytes
XP_518767
2177
240619
S529
Q
T
T
P
E
D
H
S
G
N
H
K
N
S
L
Rhesus Macaque
Macaca mulatta
XP_001095348
2107
232862
S495
Q
P
D
V
V
Q
R
S
H
T
V
P
Y
P
D
Dog
Lupus familis
XP_541124
2192
241439
P532
P
D
E
H
P
E
H
P
E
H
P
K
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UGY8
2170
240072
P525
G
E
L
G
Q
T
T
P
E
D
H
K
N
G
L
Rat
Rattus norvegicus
XP_218665
2170
240113
P525
G
E
L
G
Q
T
T
P
E
D
H
K
N
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419718
2177
241948
L526
Q
T
T
P
E
D
N
L
E
S
Q
K
N
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921357
2181
240848
D541
T
T
P
E
D
C
G
D
E
P
R
L
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096888
2070
230154
F506
Y
R
D
A
I
V
E
F
R
Q
T
V
F
E
T
Honey Bee
Apis mellifera
XP_392019
2181
244055
I514
L
E
D
N
D
Y
A
I
E
N
E
R
E
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193250
1550
170185
R8
M
Q
Q
L
N
E
V
R
G
M
A
S
P
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.7
93.1
N.A.
92.8
92
N.A.
N.A.
84.8
N.A.
73.2
N.A.
22.8
32.4
N.A.
20.3
Protein Similarity:
100
99.9
96.2
96.1
N.A.
96
95.8
N.A.
N.A.
92.4
N.A.
84.1
N.A.
41.4
52.6
N.A.
35.8
P-Site Identity:
100
100
13.3
26.6
N.A.
26.6
26.6
N.A.
N.A.
66.6
N.A.
13.3
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
13.3
46.6
N.A.
40
40
N.A.
N.A.
80
N.A.
20
N.A.
0
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
28
0
19
28
0
10
0
19
0
0
0
0
10
% D
% Glu:
0
28
10
10
28
19
10
0
55
0
10
0
10
19
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
19
0
0
19
0
0
10
0
28
0
0
0
0
19
0
% G
% His:
0
0
0
10
0
0
28
0
10
10
37
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% K
% Leu:
10
0
19
10
0
0
0
10
0
0
0
10
0
0
64
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
10
0
0
28
0
0
46
0
0
% N
% Pro:
10
10
10
28
10
0
0
28
0
10
10
10
19
10
10
% P
% Gln:
37
10
10
0
19
10
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
10
10
10
0
10
10
0
10
10
% R
% Ser:
0
0
0
0
0
0
0
28
0
10
0
10
10
46
0
% S
% Thr:
10
37
28
0
0
19
19
0
0
10
10
0
0
0
10
% T
% Val:
0
0
0
10
10
10
10
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _