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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM72A All Species: 22.4
Human Site: S143 Identified Species: 54.76
UniProt: Q5TYM5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TYM5 NP_001116640.1 149 16619 S143 D E D V L N I S A E E C I R _
Chimpanzee Pan troglodytes XP_001164088 120 13361
Rhesus Macaque Macaca mulatta XP_001089470 149 16511 S143 D E D V L N I S A E E C I R _
Dog Lupus familis XP_849100 149 16642 S143 D E D T L D I S A E E C I R _
Cat Felis silvestris
Mouse Mus musculus Q8BFZ8 149 16608 S143 D E E T L E I S A E E Y I R _
Rat Rattus norvegicus A1KXW8 149 16738 S143 D E E M L E I S A E E Y I R _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520328 76 8439
Chicken Gallus gallus XP_417970 149 16478 S143 D E D M S C I S E E E Y I R _
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013563 147 16436 S141 D E S L E N F S E E E Y L R _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788028 67 7347
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 69.8 94.6 N.A. 89.9 89.2 N.A. 44.9 76.5 N.A. 65.7 N.A. N.A. N.A. N.A. 24.8
Protein Similarity: 100 80.5 74.5 96.6 N.A. 93.2 92.6 N.A. 48.3 88.5 N.A. 81.2 N.A. N.A. N.A. N.A. 33.5
P-Site Identity: 100 0 100 85.7 N.A. 71.4 71.4 N.A. 0 64.2 N.A. 50 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 0 100 92.8 N.A. 78.5 85.7 N.A. 0 71.4 N.A. 64.2 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 30 0 0 0 % C
% Asp: 70 0 40 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 70 20 0 10 20 0 0 20 70 70 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 60 0 0 0 0 0 60 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 50 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % R
% Ser: 0 0 10 0 10 0 0 70 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 40 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % _