KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKRD45
All Species:
10
Human Site:
T250
Identified Species:
31.43
UniProt:
Q5TZF3
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TZF3
NP_940895.1
282
31810
T250
Q
Q
L
E
D
I
V
T
P
I
F
T
K
M
T
Chimpanzee
Pan troglodytes
XP_001148842
266
30012
T234
Q
Q
L
E
D
I
V
T
P
I
F
T
K
M
T
Rhesus Macaque
Macaca mulatta
XP_001101749
266
30030
T234
Q
Q
L
E
D
T
V
T
P
I
F
A
K
M
T
Dog
Lupus familis
XP_853964
321
36083
N288
T
H
L
E
A
S
I
N
E
L
S
E
Q
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q810N6
248
27716
E215
E
W
L
E
S
H
P
E
A
S
I
S
E
I
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002660907
224
25051
F193
R
T
A
T
A
Q
D
F
I
E
Q
K
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783791
274
30568
E243
S
N
P
N
A
S
I
E
D
F
R
K
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22265
373
41261
T336
R
V
G
D
D
G
K
T
I
E
Y
L
V
K
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
91.1
76.3
N.A.
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
35.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
93.9
92.5
78.8
N.A.
76.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
86.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
38
0
0
0
13
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
50
0
13
0
13
0
0
0
0
0
0
% D
% Glu:
13
0
0
63
0
0
0
25
13
25
0
13
13
13
13
% E
% Phe:
0
0
0
0
0
0
0
13
0
13
38
0
0
0
13
% F
% Gly:
0
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
25
25
0
25
38
13
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
25
50
25
0
% K
% Leu:
0
0
63
0
0
0
0
0
0
13
0
13
0
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
0
% M
% Asn:
0
13
0
13
0
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
13
0
38
0
0
0
0
0
0
% P
% Gln:
38
38
0
0
0
13
0
0
0
0
13
0
25
0
13
% Q
% Arg:
25
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% R
% Ser:
13
0
0
0
13
25
0
0
0
13
13
13
0
0
0
% S
% Thr:
13
13
0
13
0
13
0
50
0
0
0
25
0
0
38
% T
% Val:
0
13
0
0
0
0
38
0
0
0
0
0
13
0
0
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _