KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3C
All Species:
7.88
Human Site:
S452
Identified Species:
17.33
UniProt:
Q5U5Q3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5Q3
NP_057710.3
659
69366
S452
D
S
S
S
S
L
G
S
G
S
T
D
S
Y
F
Chimpanzee
Pan troglodytes
XP_523137
572
58958
P377
P
A
P
P
P
G
A
P
L
I
W
A
Q
F
E
Rhesus Macaque
Macaca mulatta
XP_001096989
464
49865
N282
T
S
P
F
S
T
G
N
F
W
F
G
D
T
L
Dog
Lupus familis
XP_533399
485
52261
N303
T
S
P
F
S
T
G
N
F
W
F
G
D
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q05A36
652
68555
S445
D
S
S
S
S
L
G
S
G
S
T
D
S
Y
F
Rat
Rattus norvegicus
NP_001100847
464
49836
N282
T
S
P
F
S
T
G
N
F
W
F
G
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509290
537
58400
F351
D
F
S
P
T
S
P
F
S
T
G
N
F
W
F
Chicken
Gallus gallus
XP_418202
443
47323
S261
D
A
P
A
P
L
G
S
E
E
C
D
F
G
F
Frog
Xenopus laevis
A1L3F4
507
54145
T325
T
G
I
S
P
D
C
T
D
L
T
F
E
S
G
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
F354
T
F
E
S
S
P
G
F
D
P
T
P
A
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175528
491
52555
R309
N
S
F
T
S
T
A
R
S
A
Y
N
L
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23
70.4
67.3
N.A.
93
70.1
N.A.
68.1
40.6
48.7
27
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
36.1
70.4
70.1
N.A.
93.9
70.2
N.A.
72.5
48.2
56.7
41.2
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
0
20
20
N.A.
100
20
N.A.
20
40
13.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
26.6
26.6
N.A.
100
26.6
N.A.
46.6
53.3
20
33.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
10
0
0
19
0
0
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
37
0
0
0
0
10
0
0
19
0
0
28
28
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
10
0
0
10
0
10
% E
% Phe:
0
19
10
28
0
0
0
19
28
0
28
10
19
19
37
% F
% Gly:
0
10
0
0
0
10
64
0
19
0
10
28
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
28
0
0
10
10
0
0
10
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
28
0
0
0
19
0
0
10
% N
% Pro:
10
0
46
19
28
10
10
10
0
10
0
10
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
55
28
37
64
10
0
28
19
19
0
0
19
10
0
% S
% Thr:
46
0
0
10
10
37
0
10
0
10
37
0
0
28
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
28
10
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _