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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3C
All Species:
10
Human Site:
S461
Identified Species:
22
UniProt:
Q5U5Q3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5Q3
NP_057710.3
659
69366
S461
S
T
D
S
Y
F
G
S
N
R
L
A
D
F
S
Chimpanzee
Pan troglodytes
XP_523137
572
58958
S386
I
W
A
Q
F
E
R
S
P
G
G
G
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001096989
464
49865
S291
W
F
G
D
T
L
P
S
V
G
S
E
D
L
A
Dog
Lupus familis
XP_533399
485
52261
S312
W
F
G
D
T
L
P
S
V
G
S
E
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q05A36
652
68555
S454
S
T
D
S
Y
F
G
S
N
R
L
A
D
F
S
Rat
Rattus norvegicus
NP_001100847
464
49836
S291
W
F
G
D
T
L
P
S
V
G
S
E
D
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509290
537
58400
E360
T
G
N
F
W
F
G
E
T
L
P
S
V
G
T
Chicken
Gallus gallus
XP_418202
443
47323
F270
E
C
D
F
G
F
D
F
L
A
L
D
L
T
T
Frog
Xenopus laevis
A1L3F4
507
54145
D334
L
T
F
E
S
G
F
D
P
A
P
A
P
P
P
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
L363
P
T
P
A
P
P
G
L
M
W
S
Q
Y
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175528
491
52555
S318
A
Y
N
L
F
N
G
S
S
P
E
L
G
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23
70.4
67.3
N.A.
93
70.1
N.A.
68.1
40.6
48.7
27
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
36.1
70.4
70.1
N.A.
93.9
70.2
N.A.
72.5
48.2
56.7
41.2
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
6.6
13.3
13.3
N.A.
100
13.3
N.A.
13.3
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
20
20
N.A.
100
20
N.A.
46.6
26.6
13.3
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
19
0
28
10
10
37
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
28
28
0
0
10
10
0
0
0
10
46
0
10
% D
% Glu:
10
0
0
10
0
10
0
10
0
0
10
28
0
10
0
% E
% Phe:
0
28
10
19
19
37
10
10
0
0
0
0
0
19
0
% F
% Gly:
0
10
28
0
10
10
46
0
0
37
10
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
0
28
0
10
10
10
28
10
10
28
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
19
0
0
10
0
0
19
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
10
10
28
0
19
10
19
0
10
10
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
19
0
0
0
0
10
% R
% Ser:
19
0
0
19
10
0
0
64
10
0
37
10
0
0
19
% S
% Thr:
10
37
0
0
28
0
0
0
10
0
0
0
0
10
19
% T
% Val:
0
0
0
0
0
0
0
0
28
0
0
0
10
0
0
% V
% Trp:
28
10
0
0
10
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
0
0
19
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _