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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD2
All Species:
5.76
Human Site:
S607
Identified Species:
11.52
UniProt:
Q5U5R9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5R9
NP_877497.2
776
88122
S607
K
P
G
G
D
K
I
S
V
T
N
Q
N
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088322
776
88225
S607
K
P
G
G
D
K
I
S
V
T
N
Q
N
R
K
Dog
Lupus familis
XP_543924
776
88394
P607
K
P
G
G
D
K
I
P
V
T
N
Q
N
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU6
774
87768
P605
K
P
G
G
D
K
I
P
V
T
N
Q
N
R
R
Rat
Rattus norvegicus
Q5PQN1
1057
118521
A887
V
L
N
G
A
D
T
A
V
N
K
Q
N
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506979
739
84811
V580
N
Q
N
R
K
E
Y
V
Q
L
Y
I
D
F
L
Chicken
Gallus gallus
XP_424632
794
90010
P625
K
P
N
G
D
K
I
P
V
T
N
Q
N
R
K
Frog
Xenopus laevis
Q2TAS2
751
86306
N590
E
Y
V
R
L
Y
V
N
W
R
F
L
R
G
I
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
P589
K
P
N
G
K
S
I
P
V
T
Q
D
T
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
D830
K
P
G
G
A
N
I
D
V
T
N
E
N
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782992
776
87934
L607
K
P
N
G
G
D
I
L
V
T
N
K
N
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
S721
R
N
V
P
I
T
Q
S
N
K
H
E
F
V
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
92.6
N.A.
89.1
26
N.A.
80.4
80.8
22.8
22.4
N.A.
21.5
N.A.
N.A.
52.7
Protein Similarity:
100
N.A.
99
96.3
N.A.
94.7
40.4
N.A.
86
88.2
39.5
39.2
N.A.
37.8
N.A.
N.A.
69.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
33.3
N.A.
0
86.6
0
46.6
N.A.
60
N.A.
N.A.
60
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
46.6
N.A.
13.3
86.6
20
53.3
N.A.
73.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
42
17
0
9
0
0
0
9
9
0
9
% D
% Glu:
9
0
0
0
0
9
0
0
0
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% F
% Gly:
0
0
42
75
9
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
67
0
0
0
0
9
0
0
9
% I
% Lys:
67
0
0
0
17
42
0
0
0
9
9
9
0
17
42
% K
% Leu:
0
9
0
0
9
0
0
9
0
9
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
9
42
0
0
9
0
9
9
9
59
0
67
0
0
% N
% Pro:
0
67
0
9
0
0
0
34
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
9
0
9
0
9
50
0
0
9
% Q
% Arg:
9
0
0
17
0
0
0
0
0
9
0
0
9
59
17
% R
% Ser:
0
0
0
0
0
9
0
25
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
9
0
0
67
0
0
9
0
0
% T
% Val:
9
0
17
0
0
0
9
9
75
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
9
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _