KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD2
All Species:
6.36
Human Site:
T106
Identified Species:
12.73
UniProt:
Q5U5R9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5R9
NP_877497.2
776
88122
T106
D
V
R
Q
K
Q
R
T
S
M
D
A
S
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088322
776
88225
V106
D
V
R
Q
K
Q
R
V
S
M
D
A
S
S
S
Dog
Lupus familis
XP_543924
776
88394
I106
D
V
R
Q
K
Q
R
I
S
V
D
P
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU6
774
87768
M104
D
V
R
Q
K
Q
R
M
S
V
E
A
L
P
S
Rat
Rattus norvegicus
Q5PQN1
1057
118521
T179
G
I
E
C
Q
K
Q
T
S
P
Q
L
I
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506979
739
84811
L91
P
A
E
P
A
L
P
L
L
N
K
T
I
Q
N
Chicken
Gallus gallus
XP_424632
794
90010
I124
D
V
R
Q
K
Q
R
I
S
I
D
T
L
P
Q
Frog
Xenopus laevis
Q2TAS2
751
86306
A91
K
I
H
K
K
Q
G
A
G
F
L
G
C
V
R
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
A91
K
I
H
K
K
Q
G
A
G
F
L
G
C
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
S211
I
R
E
T
R
E
Q
S
E
P
S
S
G
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782992
776
87934
S96
G
T
K
E
K
G
K
S
A
E
K
R
S
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
N117
I
V
K
E
P
E
I
N
S
N
L
E
S
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
92.6
N.A.
89.1
26
N.A.
80.4
80.8
22.8
22.4
N.A.
21.5
N.A.
N.A.
52.7
Protein Similarity:
100
N.A.
99
96.3
N.A.
94.7
40.4
N.A.
86
88.2
39.5
39.2
N.A.
37.8
N.A.
N.A.
69.9
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
66.6
20
N.A.
0
60
13.3
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
93.3
80
N.A.
80
46.6
N.A.
6.6
66.6
26.6
26.6
N.A.
46.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
17
9
0
0
25
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
17
0
0
% C
% Asp:
42
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% D
% Glu:
0
0
25
17
0
17
0
0
9
9
9
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
9
17
0
17
0
0
17
9
0
0
% G
% His:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
25
0
0
0
0
9
17
0
9
0
0
17
0
0
% I
% Lys:
17
0
17
17
67
9
9
0
0
0
17
0
0
17
0
% K
% Leu:
0
0
0
0
0
9
0
9
9
0
25
9
25
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
17
0
0
0
9
9
% N
% Pro:
9
0
0
9
9
0
9
0
0
17
0
9
0
17
0
% P
% Gln:
0
0
0
42
9
59
17
0
0
0
9
0
0
9
9
% Q
% Arg:
0
9
42
0
9
0
42
0
0
0
0
9
0
0
17
% R
% Ser:
0
0
0
0
0
0
0
17
59
0
9
9
34
34
50
% S
% Thr:
0
9
0
9
0
0
0
17
0
0
0
17
0
0
9
% T
% Val:
0
50
0
0
0
0
0
9
0
17
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _