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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD2
All Species:
28.48
Human Site:
T676
Identified Species:
56.97
UniProt:
Q5U5R9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5R9
NP_877497.2
776
88122
T676
M
H
A
L
Q
R
S
T
Q
Y
D
G
Y
A
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088322
776
88225
T676
M
H
A
L
Q
R
S
T
Q
Y
D
G
Y
A
K
Dog
Lupus familis
XP_543924
776
88394
T676
M
Y
A
L
Q
R
S
T
Q
Y
D
G
Y
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU6
774
87768
T674
M
H
A
L
Q
R
S
T
Q
Y
D
G
Y
A
K
Rat
Rattus norvegicus
Q5PQN1
1057
118521
T956
W
K
E
L
E
K
N
T
E
Y
K
G
E
Y
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506979
739
84811
K646
T
Q
Y
E
G
Y
V
K
T
D
L
T
I
R
Y
Chicken
Gallus gallus
XP_424632
794
90010
T694
M
S
A
L
Q
R
S
T
Q
Y
E
G
Y
Q
K
Frog
Xenopus laevis
Q2TAS2
751
86306
V656
C
T
T
D
S
N
I
V
K
W
F
W
K
A
V
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
T658
I
N
D
W
K
S
N
T
R
L
K
H
C
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
T899
V
K
D
W
R
E
N
T
L
Y
K
G
D
Y
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782992
776
87934
T676
Y
E
E
L
E
K
V
T
L
Y
D
G
F
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
T790
F
K
S
L
R
S
V
T
K
Y
V
G
G
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
92.6
N.A.
89.1
26
N.A.
80.4
80.8
22.8
22.4
N.A.
21.5
N.A.
N.A.
52.7
Protein Similarity:
100
N.A.
99
96.3
N.A.
94.7
40.4
N.A.
86
88.2
39.5
39.2
N.A.
37.8
N.A.
N.A.
69.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
26.6
N.A.
0
80
6.6
6.6
N.A.
20
N.A.
N.A.
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
53.3
N.A.
0
86.6
20
40
N.A.
40
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
0
0
0
0
0
0
0
0
0
42
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
17
9
0
0
0
0
0
9
42
0
9
9
0
% D
% Glu:
0
9
17
9
17
9
0
0
9
0
9
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
75
9
0
0
% G
% His:
0
25
0
0
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
9
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% I
% Lys:
0
25
0
0
9
17
0
9
17
0
25
0
9
0
50
% K
% Leu:
0
0
0
67
0
0
0
0
17
9
9
0
0
0
0
% L
% Met:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
25
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
9
0
0
42
0
0
0
42
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
17
42
0
0
9
0
0
0
0
9
0
% R
% Ser:
0
9
9
0
9
17
42
0
0
0
0
0
0
0
9
% S
% Thr:
9
9
9
0
0
0
0
84
9
0
0
9
0
9
0
% T
% Val:
9
0
0
0
0
0
25
9
0
0
9
0
0
0
9
% V
% Trp:
9
0
0
17
0
0
0
0
0
9
0
9
0
0
9
% W
% Tyr:
9
9
9
0
0
9
0
0
0
75
0
0
42
17
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _