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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD2
All Species:
16.97
Human Site:
T733
Identified Species:
33.94
UniProt:
Q5U5R9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5R9
NP_877497.2
776
88122
T733
F
K
I
S
K
N
E
T
S
T
N
C
L
P
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088322
776
88225
T733
F
K
I
S
K
N
E
T
S
T
N
W
L
P
V
Dog
Lupus familis
XP_543924
776
88394
T733
F
K
I
S
K
N
E
T
S
T
N
W
L
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU6
774
87768
T731
F
K
I
S
K
N
E
T
S
T
N
W
L
P
V
Rat
Rattus norvegicus
Q5PQN1
1057
118521
G1014
L
V
I
Q
S
T
G
G
G
E
S
Y
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506979
739
84811
S697
K
I
S
K
N
E
T
S
T
N
W
L
P
V
A
Chicken
Gallus gallus
XP_424632
794
90010
A751
F
K
I
S
K
S
E
A
S
T
S
W
L
P
V
Frog
Xenopus laevis
Q2TAS2
751
86306
A708
F
T
I
H
Q
I
D
A
S
T
N
N
L
P
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
A722
F
T
I
H
Q
I
D
A
S
T
N
N
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
G963
M
F
T
I
E
K
W
G
T
P
N
N
F
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782992
776
87934
T733
F
K
I
I
R
V
D
T
S
S
N
M
L
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
H849
K
I
S
L
L
G
S
H
D
S
D
D
L
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
92.6
N.A.
89.1
26
N.A.
80.4
80.8
22.8
22.4
N.A.
21.5
N.A.
N.A.
52.7
Protein Similarity:
100
N.A.
99
96.3
N.A.
94.7
40.4
N.A.
86
88.2
39.5
39.2
N.A.
37.8
N.A.
N.A.
69.9
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
26.6
N.A.
0
73.3
46.6
46.6
N.A.
13.3
N.A.
N.A.
53.3
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
33.3
N.A.
13.3
86.6
60
60
N.A.
26.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
25
0
9
0
9
9
0
0
0
% D
% Glu:
0
0
0
0
9
9
42
0
0
9
0
0
0
0
0
% E
% Phe:
67
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
9
9
17
9
0
0
0
0
0
0
% G
% His:
0
0
0
17
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
17
75
17
0
17
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
50
0
9
42
9
0
0
0
0
0
0
0
0
17
% K
% Leu:
9
0
0
9
9
0
0
0
0
0
0
9
84
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
0
0
0
9
34
0
0
0
9
67
25
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
9
92
0
% P
% Gln:
0
0
0
9
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
17
42
9
9
9
9
67
17
17
0
0
0
0
% S
% Thr:
0
17
9
0
0
9
9
42
17
59
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
0
0
0
0
0
0
0
9
50
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
9
34
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _