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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD2
All Species:
18.18
Human Site:
Y499
Identified Species:
36.36
UniProt:
Q5U5R9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5R9
NP_877497.2
776
88122
Y499
S
S
F
K
C
D
N
Y
S
E
F
R
L
V
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088322
776
88225
Y499
S
S
F
K
C
D
N
Y
S
E
F
R
L
V
G
Dog
Lupus familis
XP_543924
776
88394
Y499
S
S
F
K
C
D
N
Y
S
E
F
R
L
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU6
774
87768
Y497
S
S
F
K
C
D
N
Y
S
E
F
R
L
V
G
Rat
Rattus norvegicus
Q5PQN1
1057
118521
V705
F
L
P
V
I
E
S
V
N
P
C
L
I
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506979
739
84811
G473
R
L
V
G
I
L
M
G
L
A
V
Y
N
S
N
Chicken
Gallus gallus
XP_424632
794
90010
Y517
S
S
F
K
C
D
N
Y
S
E
F
R
L
V
G
Frog
Xenopus laevis
Q2TAS2
751
86306
L483
S
A
V
N
P
E
H
L
S
Y
F
H
F
V
G
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
I481
F
Q
Y
S
R
D
D
I
Y
T
L
Q
I
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
K705
E
W
F
Y
L
L
S
K
E
M
F
N
P
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782992
776
87934
N498
N
P
A
C
T
D
C
N
Q
E
F
N
L
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
L612
S
K
G
K
N
S
Q
L
E
L
Y
Y
L
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
92.6
N.A.
89.1
26
N.A.
80.4
80.8
22.8
22.4
N.A.
21.5
N.A.
N.A.
52.7
Protein Similarity:
100
N.A.
99
96.3
N.A.
94.7
40.4
N.A.
86
88.2
39.5
39.2
N.A.
37.8
N.A.
N.A.
69.9
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
0
100
33.3
6.6
N.A.
13.3
N.A.
N.A.
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
33.3
N.A.
0
100
53.3
33.3
N.A.
20
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
9
42
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
59
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
17
0
0
17
50
0
0
0
0
0
% E
% Phe:
17
0
50
0
0
0
0
0
0
0
67
0
9
9
0
% F
% Gly:
0
0
9
9
0
0
0
9
0
0
0
0
0
0
67
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
9
0
0
0
0
17
0
0
% I
% Lys:
0
9
0
50
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
17
0
0
9
17
0
17
9
9
9
9
59
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
0
9
9
0
42
9
9
0
0
17
9
9
9
% N
% Pro:
0
9
9
0
9
0
0
0
0
9
0
0
9
0
9
% P
% Gln:
0
9
0
0
0
0
9
0
9
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
9
0
0
0
0
0
0
42
0
0
0
% R
% Ser:
59
42
0
9
0
9
17
0
50
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
17
9
0
0
0
9
0
0
9
0
0
59
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
42
9
9
9
17
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _