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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf34
All Species:
10.91
Human Site:
S124
Identified Species:
30
UniProt:
Q5U5X8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5X8
NP_116218.1
452
46792
S124
A
P
A
G
P
A
K
S
V
L
K
S
A
E
G
Chimpanzee
Pan troglodytes
XP_001138665
452
46685
S124
A
P
A
G
P
A
K
S
V
L
K
S
A
E
G
Rhesus Macaque
Macaca mulatta
XP_001105966
452
46810
S124
A
P
A
G
P
A
K
S
V
L
K
S
A
E
G
Dog
Lupus familis
XP_854396
751
77399
K420
T
A
P
T
G
P
A
K
S
V
L
K
S
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGH4
453
47214
V124
P
A
G
H
P
K
S
V
L
K
S
V
E
G
K
Rat
Rattus norvegicus
NP_001102537
452
47220
V124
P
A
G
H
T
K
S
V
L
K
S
V
E
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231228
424
44989
L125
A
E
G
K
R
T
K
L
S
P
A
Q
A
G
V
Frog
Xenopus laevis
NP_001087653
645
69762
S188
P
P
G
L
Q
H
P
S
T
L
Q
H
P
Q
G
Zebra Danio
Brachydanio rerio
NP_001119926
527
56134
A133
C
S
S
F
V
P
S
A
K
G
V
L
K
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.2
53
N.A.
91.1
89.8
N.A.
N.A.
62.8
25.8
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.6
55.3
N.A.
94
92.9
N.A.
N.A.
71
41.2
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
6.6
0
N.A.
N.A.
20
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
6.6
N.A.
N.A.
20
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
34
34
0
0
34
12
12
0
0
12
0
45
12
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
0
23
34
12
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
45
34
12
0
0
0
0
12
0
0
0
34
45
% G
% His:
0
0
0
23
0
12
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
23
45
12
12
23
34
12
12
0
23
% K
% Leu:
0
0
0
12
0
0
0
12
23
45
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
34
45
12
0
45
23
12
0
0
12
0
0
12
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
12
12
0
12
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
12
0
0
0
34
45
23
0
23
34
12
0
12
% S
% Thr:
12
0
0
12
12
12
0
0
12
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
23
34
12
12
23
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _