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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR157
All Species:
8.18
Human Site:
S221
Identified Species:
20
UniProt:
Q5UAW9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5UAW9
NP_079256.4
335
36623
S221
H
R
L
L
R
H
S
S
M
A
D
K
K
L
V
Chimpanzee
Pan troglodytes
XP_001167246
265
29511
L157
S
S
T
A
D
K
K
L
V
L
I
P
L
I
F
Rhesus Macaque
Macaca mulatta
XP_001118360
246
27661
A138
I
P
L
V
I
T
V
A
A
V
A
L
K
K
I
Dog
Lupus familis
XP_850584
420
45058
S307
H
Q
L
Q
R
R
A
S
V
A
D
K
K
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C206
330
36325
T221
Q
L
Q
R
G
S
S
T
S
T
A
D
K
K
L
Rat
Rattus norvegicus
Q5FVG1
330
36669
T221
Q
L
Q
R
G
S
P
T
S
M
A
D
K
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518486
206
22727
K98
R
T
S
I
A
D
K
K
L
I
L
I
P
I
I
Chicken
Gallus gallus
XP_417598
336
37112
T219
T
P
A
P
S
S
W
T
S
T
A
D
K
K
L
Frog
Xenopus laevis
NP_001085567
323
36475
V215
P
I
L
A
T
S
P
V
N
Q
P
R
T
I
A
Zebra Danio
Brachydanio rerio
NP_001029346
325
36676
S216
T
S
N
P
V
S
N
S
L
S
S
I
A
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.3
62
69.7
N.A.
85.3
83.2
N.A.
46.8
64.8
60.2
55.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.5
65.9
74.7
N.A.
89.8
88.6
N.A.
52.8
77.9
76.1
71
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
60
N.A.
13.3
6.6
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
33.3
86.6
N.A.
26.6
20
N.A.
26.6
20
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
20
10
0
10
10
10
20
40
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
20
30
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% G
% His:
20
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
10
10
0
0
0
0
10
10
20
0
30
30
% I
% Lys:
0
0
0
0
0
10
20
10
0
0
0
20
60
40
0
% K
% Leu:
0
20
40
10
0
0
0
10
20
10
10
10
10
20
30
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
10
20
0
20
0
0
20
0
0
0
10
10
10
0
0
% P
% Gln:
20
10
20
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
10
0
20
20
10
0
0
0
0
0
10
0
0
10
% R
% Ser:
10
20
10
0
10
50
20
30
30
10
10
0
0
0
0
% S
% Thr:
20
10
10
0
10
10
0
30
0
20
0
0
10
0
0
% T
% Val:
0
0
0
10
10
0
10
10
20
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _