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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
28.48
Human Site:
S225
Identified Species:
62.67
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
S225
D
F
E
E
A
F
P
S
Q
G
T
K
R
P
G
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
S225
D
F
E
E
A
F
P
S
Q
G
T
K
R
P
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
S225
D
F
E
E
A
F
P
S
Q
G
T
K
R
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
S225
D
F
E
E
A
F
P
S
Q
G
T
K
R
P
G
Rat
Rattus norvegicus
NP_001099283
832
94411
S225
D
F
E
E
A
F
P
S
Q
G
T
K
R
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
S224
D
F
E
E
A
F
P
S
Q
G
T
K
R
H
G
Chicken
Gallus gallus
Q5ZLD7
831
93687
S224
D
F
E
E
A
F
P
S
Q
G
T
K
R
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
A228
D
F
K
E
A
F
S
A
K
P
S
S
Q
N
Q
Honey Bee
Apis mellifera
XP_623283
834
95369
G225
D
F
K
Q
A
F
S
G
Q
N
P
K
Y
F
N
Nematode Worm
Caenorhab. elegans
P34561
798
89225
T215
D
L
K
N
A
F
Q
T
G
Q
L
S
D
R
I
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
N229
D
F
E
E
S
F
A
N
Q
G
S
R
P
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
33.3
40
20
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
66.6
53.3
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
91
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
73
82
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
91
0
0
0
100
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
73
0
0
0
0
73
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
28
0
0
0
0
0
10
0
0
73
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
10
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
64
0
0
10
10
0
10
55
0
% P
% Gln:
0
0
0
10
0
0
10
0
82
10
0
0
10
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
64
10
0
% R
% Ser:
0
0
0
0
10
0
19
64
0
0
19
19
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
64
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _