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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
22.12
Human Site:
S381
Identified Species:
48.67
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
S381
K
L
E
S
P
P
P
S
T
N
P
F
L
E
D
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
S381
K
L
E
S
P
P
P
S
T
N
P
F
L
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
S381
K
L
E
C
P
P
P
S
T
N
P
F
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
S381
K
L
E
S
P
P
P
S
T
N
P
F
L
E
D
Rat
Rattus norvegicus
NP_001099283
832
94411
S381
K
L
E
S
P
P
P
S
T
N
P
F
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
N380
K
L
E
A
P
T
P
N
T
N
P
F
L
E
D
Chicken
Gallus gallus
Q5ZLD7
831
93687
S380
K
P
E
A
P
P
P
S
T
N
P
F
L
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
P386
K
A
R
V
L
A
E
P
T
T
T
D
G
A
V
Honey Bee
Apis mellifera
XP_623283
834
95369
M377
N
K
K
N
T
T
D
M
T
D
N
K
V
P
G
Nematode Worm
Caenorhab. elegans
P34561
798
89225
F366
I
W
S
V
F
D
T
F
L
D
V
F
I
N
A
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
V384
S
S
A
G
N
V
A
V
A
E
E
S
T
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
80
86.6
N.A.
N.A.
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
13.3
33.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
19
0
10
10
0
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
19
0
10
0
0
64
% D
% Glu:
0
0
64
0
0
0
10
0
0
10
10
0
0
64
0
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
73
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
73
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
55
0
0
10
0
0
0
10
0
0
0
64
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
10
0
0
10
0
64
10
0
0
10
0
% N
% Pro:
0
10
0
0
64
55
64
10
0
0
64
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
37
0
0
0
55
0
0
0
10
0
0
10
% S
% Thr:
0
0
0
0
10
19
10
0
82
10
10
0
10
0
0
% T
% Val:
0
0
0
19
0
10
0
10
0
0
10
0
10
10
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _