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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
30.3
Human Site:
S435
Identified Species:
66.67
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
S435
H
L
Y
V
Y
I
E
S
Q
D
K
N
L
G
E
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
S435
H
L
Y
V
Y
I
E
S
Q
D
K
N
L
G
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
S435
H
L
Y
V
Y
I
E
S
Q
D
K
N
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
S435
H
L
Y
V
Y
I
E
S
Q
D
K
N
L
S
E
Rat
Rattus norvegicus
NP_001099283
832
94411
S435
H
L
Y
V
Y
I
E
S
Q
D
K
N
L
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
S434
H
L
N
V
Y
I
E
S
Q
D
K
N
L
G
E
Chicken
Gallus gallus
Q5ZLD7
831
93687
S434
H
L
Y
V
Y
I
E
S
Q
D
K
N
L
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
A439
S
R
E
P
Y
K
F
A
E
A
K
T
T
V
Y
Honey Bee
Apis mellifera
XP_623283
834
95369
K432
N
L
A
D
L
M
D
K
F
V
S
D
S
K
T
Nematode Worm
Caenorhab. elegans
P34561
798
89225
A456
Y
A
T
S
C
L
V
A
F
L
P
S
L
G
S
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
S440
H
L
H
I
Y
I
Q
S
Q
D
R
N
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
13.3
6.6
13.3
60
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
26.6
33.3
40
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
19
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
73
0
10
0
0
10
% D
% Glu:
0
0
10
0
0
0
64
0
10
0
0
0
0
0
64
% E
% Phe:
0
0
0
0
0
0
10
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% G
% His:
73
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
73
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
0
0
73
0
0
10
0
% K
% Leu:
0
82
0
0
10
10
0
0
0
10
0
0
82
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
73
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
73
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
10
0
0
0
73
0
0
10
10
10
37
10
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
10
% T
% Val:
0
0
0
64
0
0
10
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
55
0
82
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _