KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
30
Human Site:
S514
Identified Species:
66
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
S514
E
Y
A
W
K
I
L
S
G
N
L
P
K
T
T
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
S514
E
Y
A
W
K
I
L
S
G
N
L
P
K
T
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
S514
E
Y
A
W
K
I
L
S
G
N
L
P
K
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
S514
E
Y
A
W
K
I
L
S
G
N
L
P
K
T
S
Rat
Rattus norvegicus
NP_001099283
832
94411
S514
E
Y
A
W
K
I
L
S
G
N
L
P
K
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
S513
E
Y
A
C
K
I
L
S
G
N
L
P
K
M
T
Chicken
Gallus gallus
Q5ZLD7
831
93687
S513
E
Y
A
W
K
I
L
S
G
N
L
P
K
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
V511
S
S
S
I
G
K
S
V
S
L
L
T
R
D
M
Honey Bee
Apis mellifera
XP_623283
834
95369
Q503
E
Y
A
L
K
I
L
Q
N
N
L
P
K
I
G
Nematode Worm
Caenorhab. elegans
P34561
798
89225
F572
C
V
G
D
E
S
P
F
I
G
S
M
R
A
H
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
T519
V
F
A
N
R
L
L
T
N
N
L
P
K
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
86.6
100
N.A.
N.A.
N.A.
6.6
66.6
0
40
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
100
N.A.
N.A.
N.A.
20
66.6
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
82
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
73
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
64
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
73
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
73
10
0
0
0
0
0
0
82
0
0
% K
% Leu:
0
0
0
10
0
10
82
0
0
10
91
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% M
% Asn:
0
0
0
10
0
0
0
0
19
82
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
82
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
19
0
0
% R
% Ser:
10
10
10
0
0
10
10
64
10
0
10
0
0
10
19
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
0
55
46
% T
% Val:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _