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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS53
All Species:
34.55
Human Site:
S658
Identified Species:
76
UniProt:
Q5VIR6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VIR6
NP_001121631.1
699
79653
S658
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Q
Chimpanzee
Pan troglodytes
XP_001151796
699
79606
S658
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868404
697
79456
A657
P
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCB4
832
94405
S658
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Q
Rat
Rattus norvegicus
NP_001099283
832
94411
S658
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513747
831
94249
S657
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Q
Chicken
Gallus gallus
Q5ZLD7
831
93687
S657
I
I
R
D
N
L
A
S
T
R
K
Y
F
T
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608825
887
99804
S655
T
I
R
D
T
L
A
S
S
R
K
Y
F
T
Q
Honey Bee
Apis mellifera
XP_623283
834
95369
S663
T
I
R
D
R
L
S
S
C
R
K
Y
F
T
Q
Nematode Worm
Caenorhab. elegans
P34561
798
89225
A750
L
T
S
R
I
G
G
A
L
P
T
V
G
S
A
Sea Urchin
Strong. purpuratus
XP_796587
943
107704
S669
V
I
R
D
N
L
A
S
A
R
K
Y
F
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98
N.A.
81.3
80.8
N.A.
76.1
78
N.A.
N.A.
N.A.
31.7
47.7
26.3
48.9
Protein Similarity:
100
100
N.A.
98.5
N.A.
82.9
82.4
N.A.
79.9
80.3
N.A.
N.A.
N.A.
48.7
61.9
44.6
59.6
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
80
73.3
0
86.6
P-Site Similarity:
100
100
N.A.
40
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
80
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
73
19
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
82
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
82
10
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
55
91
10
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
82
10
0
0
0
% K
% Leu:
10
0
0
0
0
82
10
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
64
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% Q
% Arg:
0
0
82
19
10
0
0
0
0
82
10
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
10
82
19
0
0
0
0
10
0
% S
% Thr:
19
10
0
0
10
0
0
0
55
10
10
0
0
82
10
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
82
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _