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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS53 All Species: 31.82
Human Site: T228 Identified Species: 70
UniProt: Q5VIR6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VIR6 NP_001121631.1 699 79653 T228 E A F P S Q G T K R P G G P S
Chimpanzee Pan troglodytes XP_001151796 699 79606 T228 E A F P S Q G T K R P G G P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_868404 697 79456 T228 E A F P S Q G T K R P G G P S
Cat Felis silvestris
Mouse Mus musculus Q8CCB4 832 94405 T228 E A F P S Q G T K R P G G P S
Rat Rattus norvegicus NP_001099283 832 94411 T228 E A F P S Q G T K R P G G P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513747 831 94249 T227 E A F P S Q G T K R H G G P S
Chicken Gallus gallus Q5ZLD7 831 93687 T227 E A F P S Q G T K R P G G P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608825 887 99804 S231 E A F S A K P S S Q N Q H R L
Honey Bee Apis mellifera XP_623283 834 95369 P228 Q A F S G Q N P K Y F N Q L T
Nematode Worm Caenorhab. elegans P34561 798 89225 L218 N A F Q T G Q L S D R I T D M
Sea Urchin Strong. purpuratus XP_796587 943 107704 S232 E S F A N Q G S R P I G N M R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 98 N.A. 81.3 80.8 N.A. 76.1 78 N.A. N.A. N.A. 31.7 47.7 26.3 48.9
Protein Similarity: 100 100 N.A. 98.5 N.A. 82.9 82.4 N.A. 79.9 80.3 N.A. N.A. N.A. 48.7 61.9 44.6 59.6
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 100 N.A. N.A. N.A. 20 26.6 13.3 33.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 100 N.A. N.A. N.A. 46.6 40 20 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 91 0 10 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % D
% Glu: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 100 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 73 0 0 0 0 73 64 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 73 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 10 0 0 0 10 0 10 0 0 0 10 10 10 0 0 % N
% Pro: 0 0 0 64 0 0 10 10 0 10 55 0 0 64 0 % P
% Gln: 10 0 0 10 0 82 10 0 0 10 0 10 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 64 10 0 0 10 10 % R
% Ser: 0 10 0 19 64 0 0 19 19 0 0 0 0 0 64 % S
% Thr: 0 0 0 0 10 0 0 64 0 0 0 0 10 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _